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Pathways


BB

Bone Biology Pathways

BMP Pathway

BMP Pathway

BMPs (Bone Morphogenetic Proteins) are a large subclass of the TGF-Beta (Transforming Growth Factor-Beta) super family.

RANK Pathway

RANK Pathway

RANKL and its receptor RANK are key regulators of bone remodeling, and are essential for the development and activation of osteoclasts.

RANK Signaling in Osteoclasts

RANK Signaling in Osteoclasts

RANKL induces the differentiation of osteoclast precursor cells and stimulates the resorption function and survival of mature osteoclasts.