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Akt is a serine/threonine kinase that is involved in mediating various biological responses, such as inhibition of Apoptosis.
Certain cells have unique sensors, termed Death Receptors which detect the presence of extracellular death signals and rapidly ignite the cell's intrinsic apoptosis machinery.
Apoptosis is a naturally occurring proces by which a cell is directed to Programmed Cell Death.
The CTLs (Cytotoxic T Lymphocytes), also known as killer T-Cells, are produced during cell-mediated immunity designed to remove body cells displaying a foreign epitope.
FAS (also called Apo1 or CD95) is a death domain containing member of the Tumor Necrosis Factor Receptor superfamily.
Granzyme A (GzmA) activates a caspase-independent cell death pathway with morphological features of apoptosis.
Tumor protein p53 is a nuclear transcription factor that regulates the expression of a wide variety of genes involved in apoptosis, growth arrest or senescence in response to genotoxic or cellular stress.
Members of the TGF beta family play an important role in the development, homeostasis and repair of most tissues.
TNF is a multifunctional proinflammatory cytokine with effectson lipid metabolism, coagulation, insulin resistance and endothelial function.
The TNF Superfamily consists of 19 members that signal through 29 receptors that are members of the TNFR Superfamily.