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Pathways


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Apoptosis Pathways

AKT Signaling Pathway

AKT Signaling Pathway

Akt is a serine/threonine kinase that is involved in mediating various biological responses, such as inhibition of Apoptosis.

Apoptosis Through Death Receptors Pathway

Apoptosis Through Death Receptors

Certain cells have unique sensors, termed Death Receptors which detect the presence of extracellular death signals and rapidly ignite the cell's intrinsic apoptosis machinery.

Cellular Apoptosis Pathway

Cellular Apoptosis Pathway

Apoptosis is a naturally occurring proces by which a cell is directed to Programmed Cell Death.

CTL Mediated Apoptosis

CTL Mediated Apoptosis

The CTLs (Cytotoxic T Lymphocytes), also known as killer T-Cells, are produced during cell-mediated immunity designed to remove body cells displaying a foreign epitope.

Fas Signaling

Fas Signaling

FAS (also called Apo1 or CD95) is a death domain containing member of the Tumor Necrosis Factor Receptor superfamily.

Granzyme Pathway

Granzyme Pathway

Granzyme A (GzmA) activates a caspase-independent cell death pathway with morphological features of apoptosis.

p53 Mediated Apoptosis Pathway

p53 Mediated Apoptosis Pathway

Tumor protein p53 is a nuclear transcription factor that regulates the expression of a wide variety of genes involved in apoptosis, growth arrest or senescence in response to genotoxic or cellular stress.

TGF Beta Pathway

TGF Beta Pathway

Members of the TGF beta family play an important role in the development, homeostasis and repair of most tissues.

TNF Signaling Pathway

TNF Signaling Pathway

TNF is a multifunctional proinflammatory cytokine with effectson lipid metabolism, coagulation, insulin resistance and endothelial function.

TNF Superfamily Pathway

TNF Superfamily Pathway

The TNF Superfamily consists of 19 members that signal through 29 receptors that are members of the TNFR Superfamily.