Anti-Rat MHC Class II APC

Description: The HIS19 monoclonal antibody reacts with a polymorphic epitope of the rat MHC class II molecule, RT1B. This antibody reacts with all rat haplotypes except the RT1n (including BN and MAXX strains). The rat MHC class II (I-A equivalent), RT1B, is expressed by antigen presenting cells including B cells, dendritic cells and macrophages.

References:
Stet, R.J.M., J. Rozing, et.al.. 1985. HIS19: a monoclonal antibody recognizing a class II polymorphic determinant only absent on RT1n class II antigens. Transplant. Proc. 17: 182901831.
Uyama, T., J. B. Winter, et al. 1993. Replacement of dendritic cells in the airways of rat lung allografts. Am Rev Respir Dis 148(3): 760-7.
Stet, R. J., C. Thomas, et al. 1985. Graft versus host disease in the rat: Ia expression on target tissues. Adv Exp Med Biol 186: 545-54.