Anti-Rat CD45RA APC

Description: This OX33 monoclonal antibody reacts with rat CD45RA. In rats, this isoform of CD45, which is also known as leukocyte common antigen, is present only on B cells. CD45 is a type I transmembrane protein tyrosine phosphatase that exists as a variety of different isoforms due to alternative splicing.

References: Toyozaki T, Saito T, Shiraishi H, Tsukamoto Y, Takano H, Nagai T, Hiroshima K, Ohwada H, Ishiyama S, Hiroe M. Macrophage inflammatory protein-1alpha relates to the recruitment of inflammatory cells in myosin-induced autoimmune myocarditis in rats. Lab Invest. 2001 Jul;81(7):929-36. (OX33, IHC)

Quan N, Zhang Z, Demetrikopoulos MK, Kitson RP, Chambers WH, Goldfarb RH, Weiss JM. Evidence for involvement of B lymphocytes in the surveillance of lung metastasis in the rat. Cancer Res. 1999 Mar 1;59(5):1080-9. (OX33, FC)

Woollett GR, Barclay AN, Puklavec M, Williams AF. Molecular and antigenic heterogeneity of the rat leukocyte-common antigen from thymocytes and T and B lymphocytes. Eur J Immunol. 1985 Feb;15(2):168-73. (OX33, IP)