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Anti-Rat CD45.2 Purified (To be Discontinued)

Also known as: Ly5.2

Clone: HIS41

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-0450

Cat. No. Size
14-0450-82 100 ug
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Data for Anti-Rat CD45.2 Purified.

Staining of rat splenocytes with 0.06 ug Mouse IgG1 Isotype Control Purified (cat.14-4714) (open...View More

  • Data for Anti-Rat CD45.2 Purified.
Description

Description: The HIS41 monoclonal antibody reacts with all isoforms of the rat CD45 molecule, also known as Leukocyte Common Antigen (LCA). CD45 is expressed by all hematopoietic cells excluding mature erythrocytes and platelets. The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in signaling and activation of lymphocytes. HIS41 reacts with strains expressing the RT7.2 alloantigen (BUF, LOU, and WF), but not strains expressing the RT7.1 alloantigen (ACI, AO, BN, DA, DZB, LEW, MAXX, PVG, SHR, and WAG).

Details
Host Mouse
Isotype IgG1
Reactivity Rat
Conjugate Purified
Reported Applications Flow Cytometric Analysis, Immunohistochemical Staining of Frozen Tissue Sections
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
12-0450 Anti-Rat CD45.2 PE (To be Discontinued) 488 - 561 nm FC RUO
11-0450 Anti-Rat CD45.2 FITC (To be Discontinued) 488 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
11-4011 Anti-Mouse IgG FITC 488 nm FC RUO
11-4317 Streptavidin FITC 488 nm FC, ICC, IHC RUO
12-4317 Streptavidin PE 488 - 561 nm FC RUO
13-4013 Anti-Mouse IgG Biotin FC, ELISA, IHC, WB RUO
14-4714 Mouse IgG1 K Isotype Control Purified FC, ICC, IHC, IP, WB RUO
17-4317 Streptavidin APC 633 - 647 nm 660 nm FC RUO
References

References:
Kampinga, J., F.G.M. Kroese, G.H. Pol, D. Opstelten, H.G. Seijen, J.H.A. Boot, B. Roser, P. Nieuwenhuis, and R. Aspinall. 1990. RT7-defined alloantigens in rats are part of the leukocyte common antigen family. Scand. J. Immunol. 31:699-710.
Giezeman-Smits, K. M., A. Gorter, R. L. P. van Vlierberghe, J. D. H. v. Eendenburg, A. M. M. Eggermont, G. J. Fleuren, P. J. K. Kuppen. 1999. The Regulatory Role of CD45 on Rat NK Cells in Target Cell Lysis. J. Immunol. 163:71-76.
Butcher, G.W. 1987. A list of monoclonal antibodies specific for alloantigens of the rat. J. Immunogenet. 14:163-176.

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