Anti-Rat CD45 APC

Description: This OX1 monoclonal antibody recognizes a non-polymorphic determinant of rat CD45, which is also known as the leukocyte common antigen. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets. This type I transmembrane protein tyrosine phosphatase exists as a variety of different isoforms due to alternative splicing.

References: Dahlke MH, Lauth OS, Jäger MD, Roeseler T, Timrott K, Jackobs S, Neipp M, Wonigeit K, Schlitt HJ. In vivo depletion of hematopoietic stem cells in the rat by an anti-CD45 (RT7) antibody. Blood. 2002 May 15;99(10):3566-72. (OX1, FC)

Mojcik CF, Greiner DL, Goldschneider I, Lubaroff DM. Monoclonal antibodies to RT7 and LCA antigens in the rat: cell distribution and segregation analysis. Hybridoma. 1987 Oct;6(5):531-43. (OX1)

Hart DN, Fabre JW. Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain. J Exp Med. 1981 Aug 1;154(2):347-61. (OX1, IHC-F)

Sunderland CA, McMaster WR, Williams AF. Purification with monoclonal antibody of a predominant leukocyte-common antigen and glycoprotein from rat thymocytes. Eur J Immunol. 1979 Feb;9(2):155-9. (OX1)