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SKU# 17-0040
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Staining of rat splenocytes with Anti-Rat CD3 PE (cat. 12-0030) and 0.125 ug of Mouse IgG2a K...View More
Description: The OX35 monoclonal antibody reacts with rat CD4. CD4 is a co-receptor which participates in signaling through the T cell receptor by making contacts with MHC class II expressed on antigen-presenting cells (APC). CD4 is expressed in the thymus by CD4+CD8+ "double-positive" and CD4+ "single-positive" thymocytes, and by CD4+ "helper" T cells in the periphery. CD4 is a cell-surface membrane glycoprotein which contains four extracellular immunoglobulin-like domains.
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References: May E, Dorris ML, Satumtira N, Iqbal I, Rehman MI, Lightfoot E, Taurog JD. CD8 alpha beta T cells are not essential to the pathogenesis of arthritis or colitis in HLA-B27 transgenic rats. J Immunol. 2003 Jan 15;170(2):1099-105. (OX35, FC, PubMed)
Anti-Human CD3 APC
Anti-Mouse CD3e APC
Anti-Human/Non-Human Primate CD2 APC
Anti-Human CD184 (CXCR4) Functional Grade Purified
Anti-Human CD279 (PD-1) Functional Grade Purified
