Anti-Rat CD103 (Integrin alpha E) PE

Also known as: Integrin aE, ITGAE, HML1

Clone: OX62

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 12-1030

Cat. No. Size
12-1030-80 25 ug
12-1030-82 100 ug
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Data for Anti-Rat CD103 (Integrin alpha E) PE.

Staining of rat splenocytes with Anti-Rat CD4 FITC (cat. 11-0040) and 0.125 ug of Mouse IgG1 kappa...View More

  • Data for Anti-Rat CD103 (Integrin alpha E) PE.
Description

Description: The OX62 monoclonal antibody reacts with rat CD103, also known as αE2 integrin. CD103 was originally identified on rat veiled dendritic cells, and is expressed by dendritic epidermal T cells in the skin, intraepithelial lymphocytes in the small intestine and by dendritic cells associated with γδ T cells. Integrins are a family of heterodimeric proteins which contain non-covalently associated α and β transmembrane glycoproteins. Integrins function as receptors for extracellular matrix and cell-cell adhesion molecules.

Details
Host Mouse
Isotype IgG1
Reactivity Rat
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Related Products
Cat. No. Name Excite Emit Application Reg.
12-1031 Anti-Mouse CD103 (Integrin alpha E) PE 488 - 561 nm FC RUO
12-4714 Mouse IgG1 K Isotype Control PE 488 - 561 nm FC RUO
11-0040 Anti-Rat CD4 FITC 488 nm 518 nm FC RUO
12-1038 Anti-Human CD103 (Integrin alpha E) PE 488 - 561 nm 575 nm FC RUO
References

References: Brenan M, Puklavec M.The MRC OX-62 antigen: a useful marker in the purification of rat veiled cells with the biochemical properties of an integrin.J Exp Med. 1992 Jun 1;175(6):1457-65. (OX62, mAb development, FC, PubMed)

Voisine C, Hubert FX, Trinité B, Heslan M, Josien R.Two phenotypically distinct subsets of spleen dendritic cells in rats exhibit different cytokine production and T cell stimulatory activity.J Immunol. 2002 Sep 1;169(5):2284-91. (OX62, FC, PubMed)

Hubert FX, Voisine C, Louvet C, Heslan M, Josien R.Rat plasmacytoid dendritic cells are an abundant subset of MHC class II+ CD4+CD11b-OX62- and type I IFN-producing cells that exhibit selective expression of Toll-like receptors 7 and 9 and strong responsiveness to CpG.J Immunol. 2004 Jun 15;172(12):7485-94. (OX62, FC, PubMed)