Anti-Mouse V alpha 8.3 TCR FITC

Description: The B21.14 monoclonal antibody reacts with the mouse T-cell receptor (TCR) Vα8.3 chain in all mouse strains tested. Specifically, the epitope of B21.14 has been mapped to three amino acids which are unique to Vα8.3, but are not present in the other Vα8 subfamily members.

References: Pircher H, Rebaï N, Groettrup M, Grégoire C, Speiser DE, Happ MP, Palmer E, Zinkernagel RM, Hengartner H, Malissen B.Preferential positive selection of V alpha 2+ CD8+ T cells in mouse strains expressing both H-2k and T cell receptor V alpha a haplotypes: determination with a V alpha 2-specific monoclonal antibody.Eur J Immunol. 1992 Feb;22(2):399-404.

Necker A, Rebaï N, Matthes M, Jouvin-Marche E, Cazenave PA, Swarnworawong P, Palmer E, MacDonald HR, Malissen B.Monoclonal antibodies raised against engineered soluble mouse T cell receptors and specific for V alpha 8-, V beta 2- or V beta 10-bearing T cells.Eur J Immunol. 1991 Dec;21(12):3035-40.