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  • Anti-Mouse TNF alpha Alexa Fluor® 647 (To Be Discontinued. Refer to Alternative Format: APC cat. 17-7321)

Anti-Mouse TNF alpha Alexa Fluor® 647 (To Be Discontinued. Refer to Alternative Format: APC cat. 17-7321)

Also known as: Tumor Necrosis Factor alpha

Clone: MP6-XT22

RUO: For Research Use Only. Not for use in diagnostic procedures.

Attention: Discontinued. Refer to Replacement Format APC cat. 17-7321

SKU# 51-7321

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Data for Anti-Mouse TNF alpha Alexa Fluor® 647 (To Be Discontinued. Refer to Alternative Format: APC cat. 17-7321).

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  • Data for Anti-Mouse TNF alpha Alexa Fluor® 647 (To Be Discontinued. Refer to Alternative Format: APC cat. 17-7321).
Description

Description: The MP6-XT22 antibody reacts with mouse tumor necrosis factor-alpha (TNF alpha), a 17 kDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4(+) T cells. TNF alpha has cytolytic activity against a range of tumor cells and is important in immune regulation. TNF alpha forms dimers and trimers and also exists as a 26 kDa membrane-bound form.

Details
Host Rat
Isotype IgG1, kappa
Reactivity Mouse
Conjugate Alexa Fluor 647
Laser Red Laser
Emit 668 nm
Excite 633 nm
Legal Alexa Fluor® is a registered trademark of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
46-7321 Anti-Mouse TNF alpha PerCP-eFluor® 710 488 nm 710 nm FC RUO
48-7321 Anti-Mouse TNF alpha eFluor® 450 405 nm 450 nm FC RUO
11-7321 Anti-Mouse TNF alpha FITC 488 nm 518 nm FC RUO
17-7321 Anti-Mouse TNF alpha APC 633 nm 660 nm FC RUO
12-7321 Anti-Mouse TNF alpha PE 488 nm 575 nm FC RUO
14-7321 Anti-Mouse TNF alpha Purified FC, IHC RUO
16-7321 Anti-Mouse TNF alpha Functional Grade Purified FA RUO
53-7321 Anti-Mouse TNF alpha Alexa Fluor® 488 488 nm 519 nm FC RUO
19-7321 Anti-Mouse TNF alpha Cy5 633 nm 670 nm FC RUO
25-7321 Anti-Mouse TNF alpha PE-Cy7 488 nm 760 nm FC RUO
References

References: Chackerian B, Lowy DR and Schiller JT. Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies. J Clin Invest. 2001. 108(3):415-23. (IHC frozen, PubMed)

Williams RO, Mauri C, et al.Therapeutic actions of cyclosporine and anti-tumor necrosis factor alpha in collagen-induced arthritis and the effect of combination therapy. Arthritis Rheum. 1998. 41(10):1806-12. (IHC frozen, PubMed)

Hunter CA, Litton MJ, et al. Immunocytochemical detection of cytokines in the lymph nodes and brains of mice resistant or susceptible to toxoplasmic encephalitis. J Infect Dis. 1994. 170(4): 939-45.

Litton MJ, Sander B, et al. Early expression of cytokines in lymph nodes after treatment in vivo with Staphylococcus enterotoxin B. J Immunol Methods 1994. 175(1): 47-58.

Abrams JS, Roncarolo MG, et al. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol Rev. 1992. 127: 5-24.

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