Anti-Mouse/Rat IL-1 beta Purified

Description: The B122 antibody reacts with mouse and rat interleukin-1β (IL-1β), a 17 kDa factor secreted primarily by monocytes. IL-1 has effects on T-helper cells, inducing IL-2 secretion and expression of IL-2 receptors.

References:
Hogquist, K, et al. 1991. Generation of monoclonal antibodies to murine IL-1beta and demonstration of IL-1 in vivo. J. Immunol. 146: 1534-1540.
Rogers, H.W., et al. 1992. Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice. Proc Natl Acad Sci U S A. 89: 1011-5.