Anti-Mouse NK1.1 Purified

Also known as: CD161, NKR-P1C, Ly-55

Clone: PK136

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-5941

Cat. No. Size
14-5941-81 50 ug
14-5941-82 100 ug
14-5941-85 500 ug
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Data for Anti-Mouse NK1.1 Purified.

Staining of C57BL/6 splenocytes with Anti-Mouse CD3e PE (cat. 12-0031) and 0.25 ug of Mouse IgG2a K...View More

  • Data for Anti-Mouse NK1.1 Purified.
Description

Description: The PK136 monoclonal antibody reacts with mouse NK1.1, an antigen expressed by natural killer cells and a subset of T cells in the NK1.1 mouse strains including C57BL and NZB. Several commonly used laboratory mouse strains such as BALB/c, SJL, AKR, CBA, C3H and A do not express the NK1.1 antigen. For detection of NK cells in these strains the monoclonal antibody DX5 (Cat. No. 14-5971) should be used. Simultaneous staining of C57BL/6 spleen cells with PK136 and DX5 reveals coexpression of both markers by a majority of cells as well as presence of small populations of DX5+PK136- and DX5-PK136+ cells.

Details
Host Mouse
Isotype IgG2a, kappa
Reactivity Mouse
Conjugate Purified
Reported Applications Flow Cytometric Analysis, Immunoprecipitation
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
16-5941 Anti-Mouse NK1.1 Functional Grade Purified FC, FA RUO
47-5941 Anti-Mouse NK1.1 APC-eFluor® 780 633 - 647 nm 780 nm FC RUO
13-5941 Anti-Mouse NK1.1 Biotin FC RUO
48-5941 Anti-Mouse NK1.1 eFluor® 450 405 nm 450 nm FC RUO
17-5941 Anti-Mouse NK1.1 APC 633 - 647 nm 660 nm FC RUO
56-5941 Anti-Mouse NK1.1 Alexa Fluor® 700 633 - 647 nm 723 nm FC RUO
61-5941 Anti-Mouse NK1.1 PE-eFluor® 610 488 - 561 nm 607 nm FC RUO
95-5941 Anti-Mouse NK1.1 eFluor® 650NC 350 - 635 nm 650 nm FC RUO
12-5941 Anti-Mouse NK1.1 PE 488 - 561 nm 575 nm FC RUO
11-5941 Anti-Mouse NK1.1 FITC 488 nm 518 nm FC RUO
25-5941 Anti-Mouse NK1.1 PE-Cyanine7 488 - 561 nm 775 nm FC RUO
45-5941 Anti-Mouse NK1.1 PerCP-Cyanine5.5 488 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
11-4011 Anti-Mouse IgG FITC 488 nm FC RUO
12-0031 Anti-Mouse CD3e PE 488 - 561 nm 575 nm FC RUO
13-4013 Anti-Mouse IgG Biotin FC, ELISA, IHC, WB RUO
17-4317 Streptavidin APC 633 - 647 nm 660 nm FC RUO
11-4317 Streptavidin FITC 488 nm FC, ICC, IHC RUO
12-4317 Streptavidin PE 488 - 561 nm FC RUO
14-4724 Mouse IgG2a K Isotype Control Purified FC, ICC, IHC RUO
References

References: Kitaichi N, Kotake S, Morohashi T, Onoe K, Ohno S, Taylor AW. Diminution of experimental autoimmune uveoretinitis (EAU) in mice depleted of NK cells. J Leukoc Biol. 2002 Dec;72(6):1117-21. (PK136, in vivo depletion, PubMed)

Koo, G. C. and J. R. Peppard. Establishment of monoclonal anti-Nk-1.1 antibody. Hybridoma 1984. 3(3): 301-3.


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