Anti-Mouse NK1.1 PE-Cyanine7

Also known as: CD161, NKR-P1C, Ly-55

Clone: PK136

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 25-5941

Cat. No.	Size
25-5941-81	50 ug
25-5941-82	100 ug
Please inquire about custom configurations or bulk packaging.

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Staining of C57BL/6 splenocytes with Anti-Mouse CD49b (Integrin alpha 2) FITC (cat. 11-5971) and...View More

Description

Description: The PK136 monoclonal antibody reacts with mouse NK1.1, an antigen expressed by natural killer cells and a subset of T cells in the NK1.1 mouse strains including C57BL and NZB. Several commonly used laboratory mouse strains such as BALB/c, SJL, AKR, CBA, C3H and A do not express the NK1.1 antigen. For detection of NK cells in these strains the monoclonal antibody DX5 (Cat. No. 14-5971) should be used. Simultaneous staining of C57BL/6 spleen cells with PK136 and DX5 reveals coexpression of both markers by a majority of cells as well as presence of small populations of DX5+PK136- and DX5-PK136+ cells.

Details

Host	Mouse
Isotype	IgG2a, kappa
Reactivity	Mouse
Conjugate	PE-Cyanine7
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Emit	775 nm
Excite	488 - 561 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 2. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
95-5941	Anti-Mouse NK1.1 eFluor® 650NC	350 - 635 nm	650 nm	FC	RUO
48-5941	Anti-Mouse NK1.1 eFluor® 450	405 nm	450 nm	FC	RUO
56-5941	Anti-Mouse NK1.1 Alexa Fluor® 700	633 - 647 nm	723 nm	FC	RUO
45-5941	Anti-Mouse NK1.1 PerCP-Cyanine5.5	488 nm		FC	RUO
12-5941	Anti-Mouse NK1.1 PE	488 - 561 nm	575 nm	FC	RUO
16-5941	Anti-Mouse NK1.1 Functional Grade Purified			FC, FA	RUO
14-5941	Anti-Mouse NK1.1 Purified			FC, IP	RUO
47-5941	Anti-Mouse NK1.1 APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
17-5941	Anti-Mouse NK1.1 APC	633 - 647 nm	660 nm	FC	RUO
13-5941	Anti-Mouse NK1.1 Biotin			FC	RUO
11-5941	Anti-Mouse NK1.1 FITC	488 nm	518 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
11-5971	Anti-Mouse CD49b (Integrin alpha 2) FITC	488 nm	518 nm	FC	RUO
25-4724	Mouse IgG2a K Isotype Control PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO

References

References: Kitaichi N, Kotake S, Morohashi T, Onoe K, Ohno S, Taylor AW. Diminution of experimental autoimmune uveoretinitis (EAU) in mice depleted of NK cells. J Leukoc Biol. 2002 Dec;72(6):1117-21. (PK136, in vivo depletion, PubMed)

Koo, G. C. and J. R. Peppard. Establishment of monoclonal anti-Nk-1.1 antibody. Hybridoma 1984. 3(3): 301-3.

View More Products

Antigens	Area of Biology	Cell Type	Formats
NK1.1	Innate Immunity	NK & NKT Cells	PE-Cyanine7