Anti-Mouse MHC Class II (I-A) PE-Cyanine5

Also known as: MHC II, IA, MHCCII, MHCII

Clone: NIMR-4

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 15-5322

Cat. No.	Size
15-5322-81	50 ug
Please inquire about custom configurations or bulk packaging.

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Description

Description: The monoclonal antibody NIMR-4 reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells and certain epithelial cells. MHC Class II molecules are important for the selection of the TCR repertoire during the processes of positive and negative selection. MHC Class II expression is required for the positive selection of CD4+ T cells.

Details

Host	Rat
Isotype	IgG2b
Reactivity	Mouse
Conjugate	PE-Cyanine5
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Excite	488 - 561 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
12-5322	Anti-Mouse MHC Class II (I-A) PE	488 - 561 nm		FC	RUO
11-5322	Anti-Mouse MHC Class II (I-A) FITC	488 nm	518 nm	FC	RUO
13-5322	Anti-Mouse MHC Class II (I-A) Biotin (Format to be Discontinued)			FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
15-4031	Rat IgG2b K Isotype Control PE-Cyanine5	488 - 561 nm		FC	RUO

References

References: Mielenz, D., C. Vetterman, M. Hampel, C. Lang, A. Avramidou, M. Karas, and H. Jack. 2005. Lipid rafts associate with intracellular B cell receptors and exhibit a B cell stage-specific protein composition. J. Immunol. 174: 3508-3517. (NIMR-4, FC, FA, PubMed)

View More Products

Antigens	Area of Biology	Cell Type	Formats
MHC Class II (I-A)	Adaptive Immunity Innate Immunity	B Cells Dendritic Cells Macrophage & Monocyte Cells	PE-Cyanine5