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Anti-Mouse Ly-49C/I/F/H Purified

Also known as: Ly49C/I/F/H, Ly-49I, Ly-49F, Ly-49H, Ly-49CIFH, ly49, ly-49c, ly49i, ly49f, ly49h, ly49c

Clone: 14B11

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-5991

Cat. No. Size
14-5991-81 50 ug
14-5991-82 100 ug
14-5991-85 500 ug
Please inquire about custom configurations or bulk packaging.

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Data for Anti-Mouse Ly-49C/I/F/H Purified.

Staining of mouse splenocytes with Anti-Mouse Ly-49C/I/F/H PE and Anti-Mouse CD49b FITC (cat...View More

  • Data for Anti-Mouse Ly-49C/I/F/H Purified.
Description

Description: The 14B11 monoclonal antibody reacts with a subset of mouse Ly-49 receptors and recognizes a majority of mouse NK cells. This antibody reacts with 3 putative inhibitory members of the Ly-49 family, F, I, and C and one putative activating receptor, Ly-49H. 14B11 does not react with Ly-49A, B, D, or G. It is reported that 14B11 enhances the redirected lysis of FcR+ target cells by IL-2-activated NK cells.

Details
Host Golden Syrian Hamster
Isotype IgG
Reactivity Mouse
Conjugate Purified
Reported Applications Flow Cytometric Analysis, Functional Assays
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
12-5991 Anti-Mouse Ly-49C/I/F/H PE 488 - 561 nm 575 nm FC RUO
11-5991 Anti-Mouse Ly-49C/I/F/H FITC 488 nm 518 nm FC RUO
13-5991 Anti-Mouse Ly-49C/I/F/H Biotin FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
11-0491 Anti-Mouse CD49b (Integrin alpha 2) FITC 488 nm 518 nm FC RUO
11-4211 Anti-Golden Syrian Hamster IgG FITC 488 nm FC RUO
14-4914 Golden Syrian Hamster IgG Isotype Control Purified FC, IHC, IP, WB RUO
References

References: Coles MC, McMahon CW, Takizawa H, Raulet DH. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur J Immunol. 2000 Jan;30(1):236-44.

Corral L, Takizawa H, Hanke T, Jamieson AM, Raulet DH. A new monoclonal antibody reactive with several Ly49 NK cell receptors mediates redirected lysis of target cells. Hybridoma. 1999 Aug;18(4):359-66.

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