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Anti-Mouse Ly-49C/I/F/H PE

Also known as: Ly49C/I/F/H, Ly-49I, Ly-49F, Ly-49H, Ly-49CIFH, ly49, ly-49c, ly49i, ly49f, ly49h, ly49c

Clone: 14B11

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 12-5991

Cat. No. Size
12-5991-63 10 ug
12-5991-81 50 ug
12-5991-82 100 ug
12-5991-83 200 ug
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Data for Anti-Mouse Ly-49C/I/F/H PE.

Staining of C57BL/6 splenocytes with Anti-Mouse CD49b (Integrin alpha 2) FITC (cat. 11-5971) and...View More

  • Data for Anti-Mouse Ly-49C/I/F/H PE.
Description

Description: The 14B11 monoclonal antibody reacts with a subset of mouse Ly-49 receptors and recognizes a majority of mouse NK cells. This antibody reacts with 3 putative inhibitory members of the Ly-49 family, F, I, and C and one putative activating receptor, Ly-49H. 14B11 does not react with Ly-49A, B, D, or G. It is reported that 14B11 enhances the redirected lysis of FcR+ target cells by IL-2-activated NK cells.

Details
Host Golden Syrian Hamster
Isotype IgG
Reactivity Mouse
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
14-5991 Anti-Mouse Ly-49C/I/F/H Purified FC, FA RUO
13-5991 Anti-Mouse Ly-49C/I/F/H Biotin FC RUO
11-5991 Anti-Mouse Ly-49C/I/F/H FITC 488 nm 518 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
11-5971 Anti-Mouse CD49b (Integrin alpha 2) FITC 488 nm 518 nm FC RUO
12-4914 Golden Syrian Hamster IgG Isotype Control PE 488 - 561 nm 575 nm FC RUO
References

References: Coles MC, McMahon CW, Takizawa H, Raulet DH. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur J Immunol. 2000 Jan;30(1):236-44.

Corral L, Takizawa H, Hanke T, Jamieson AM, Raulet DH. A new monoclonal antibody reactive with several Ly49 NK cell receptors mediates redirected lysis of target cells. Hybridoma. 1999 Aug;18(4):359-66.

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