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Anti-Mouse Ly-49C/I/F/H Biotin

Also known as: Ly49C/I/F/H, Ly-49I, Ly-49F, Ly-49H, Ly-49CIFH, ly49, ly-49c, ly49i, ly49f, ly49h, ly49c

Clone: 14B11

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 13-5991

Cat. No. Size
13-5991-81 50 ug
13-5991-82 100 ug
13-5991-85 500 ug
Please inquire about custom configurations or bulk packaging.

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Data for Anti-Mouse Ly-49C/I/F/H Biotin.

Staining of mouse splenocytes with Anti-Mouse CD49b (Integrin alpha 2) FITC (cat. 11-5971) and...View More

  • Data for Anti-Mouse Ly-49C/I/F/H Biotin.
Description

Description: The 14B11 monoclonal antibody reacts with a subset of mouse Ly-49 receptors and recognizes a majority of mouse NK cells. This antibody reacts with 3 putative inhibitory members of the Ly-49 family, F, I, and C and one putative activating receptor, Ly-49H. 14B11 does not react with Ly-49A, B, D, or G. It is reported that 14B11 enhances the redirected lysis of FcR+ target cells by IL-2-activated NK cells.

Details
Host Golden Syrian Hamster
Isotype IgG
Reactivity Mouse
Conjugate Biotin
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
11-5991 Anti-Mouse Ly-49C/I/F/H FITC 488 nm 518 nm FC RUO
12-5991 Anti-Mouse Ly-49C/I/F/H PE 488 - 561 nm 575 nm FC RUO
14-5991 Anti-Mouse Ly-49C/I/F/H Purified FC, FA RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
11-4317 Streptavidin FITC 488 nm FC, ICC, IHC RUO
11-5971 Anti-Mouse CD49b (Integrin alpha 2) FITC 488 nm 518 nm FC RUO
12-4317 Streptavidin PE 488 - 561 nm FC RUO
13-4914 Golden Syrian Hamster IgG Isotype Control Biotin FC, IHC RUO
17-4317 Streptavidin APC 633 - 647 nm 660 nm FC RUO
References

References: Coles MC, McMahon CW, Takizawa H, Raulet DH. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur J Immunol. 2000 Jan;30(1):236-44.

Corral L, Takizawa H, Hanke T, Jamieson AM, Raulet DH. A new monoclonal antibody reactive with several Ly49 NK cell receptors mediates redirected lysis of target cells. Hybridoma. 1999 Aug;18(4):359-66.

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