Mouse IP-10 Platinum ELISA

Description: The mouse IP-10 ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of mouse IP-10. The mouse IP-10 ELISA is for research use only. Not for diagnostic or therapeutic procedures.

IP-10 is a member of the CXC subfamily of chemokines expressed by monocytes. It plays a pivotal role in immune system development and deployment. The Interferon-gamma inducible protein -10kD (IP-10) displays pleiotropic functions including stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis.
Through this inhibitory effect on neovascularization IP-10 exhibits anti-tumoral effects. It shares a common receptor, CXCR3, with the chemokine MIG, but has been shown to play a distinct role in host defense in infections. IP-10 is further involved in allergic contact dermatitis reactions and other allergic diseases. It appears during immune-mediated processes, in inflammation of the nervous system and in Alzheimer's disease.
Its involvement in the regulation of fibroproliferation following inflammatory lung injury has been described.

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