Anti-Mouse IL-6 Purified

Also known as: Interleukin-6, IL6

Clone: MP5-20F3

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-7061

Cat. No. Size
14-7061-81 50 ug
14-7061-85 500 ug
Please inquire about custom configurations or bulk packaging.

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Data for Anti-Mouse IL-6 Purified.

Mouse splenocytes (500,000 cells per well) were activated with LPS (1 ug/ml) for 48 hours in Mouse...View More

  • Data for Anti-Mouse IL-6 Purified.
Description

Description: The MP5-20F3 antibody reacts with mouse interleukin-6 (IL-6). The MP5-20F3 antibody is a neutralizing antibody. Mouse IL-6 (also known as B Cell Stimulating Factor, BCSF, and BSF-2) is a 21-28 kDa factor produced by a variety of cell types, including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, and glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6. This pleiotrophic cytokine influences the antigen-specific immune response, inflammatory response, and the development of neurons, and is a major mediator of the acute phase reaction.

Details
Host Rat
Isotype IgG1, kappa
Reactivity Mouse
Conjugate Purified
Reported Applications ELISA Capture Antibody, ELISPOT Capture Antibody, Cytokine Neutralization
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
16-7061 Anti-Mouse IL-6 Functional Grade Purified ELISA, FA RUO
11-7061 Anti-Mouse IL-6 FITC 488 nm 518 nm FC RUO
12-7061 Anti-Mouse IL-6 PE 488 - 561 nm 575 nm FC RUO
References

References:
Sander, B., I. Hoiden, et al. (1993). "Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining." J Immunol Methods 166(2): 201-14.
Starnes, H. F., Jr., M. K. Pearce, et al. (1990). "Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice" J Immunol 145(12): 4185-91.