This site will redirect to on April 7. Get details >

Anti-Mouse IL-4 Functional Grade Purified

Also known as: Interleukin-4

Clone: 11B11

RUO: For Research Use Only. Not for use in diagnostic procedures.

These products are now available on Find out more >

SKU# 16-7041

Cat. No. Size
16-7041-81 50 ug
16-7041-85 500 ug
16-7041-95 10 mg

Data for Anti-Mouse IL-4 Functional Grade Purified.

Splenocytes from 8 week old mice pre-immunized with OVA/IFA were recall-activated with OVA antigen...View More

  • Data for Anti-Mouse IL-4 Functional Grade Purified.

Description: The 11B11 antibody reacts with mouse interleukin-4 (IL-4), a 14 kD cytokine. The 11B11 antibody is a neutralizing antibody. Mouse IL-4, also known as BCDF, BCGF-1 and BSF-1, is secreted by activated Th2 and natural killer T cells, and to a lesser extent by Th1 and mast cells. IL-4 is species-specific and promotes proliferation and differentiation of B cells. IL-4, in conjunction with other signals such as CD40, induces Ig isotype switching of B cells and the upregulation of surface MHC class II and CD23.

Host Rat
Isotype IgG1, kappa
Reactivity Mouse
Conjugate Functional Grade Purified (low endo, azide-free)
Reported Applications ELISA Capture Antibody, ELISPOT, Functional Assays
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
46-7041 Anti-Mouse IL-4 PerCP-eFluor® 710 488 nm 710 nm FC RUO
17-7041 Anti-Mouse IL-4 APC 633 - 647 nm 660 nm FC RUO
25-7041 Anti-Mouse IL-4 PE-Cyanine7 488 - 561 nm 775 nm FC RUO
12-7041 Anti-Mouse IL-4 PE 488 - 561 nm 578 nm FC RUO
53-7041 Anti-Mouse IL-4 Alexa Fluor® 488 488 nm 519 nm FC RUO
14-7041 Anti-Mouse IL-4 Purified ELISA RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
13-7042 Anti-Mouse IL-4 Biotin ELISA RUO
00-4201 1X TMB Solution ELISA RUO
14-8041 Mouse IL-4 Recombinant Protein ELISA, FA RUO

References: Ciabattini A, Pettini E, Fiorino F, Pastore G, Andersen P, Pozzi G, Medaglini D. Modulation of Primary Immune Response by Different Vaccine Adjuvants. Front Immunol. 2016 Oct 17;7:427. (11B11, FC, PubMed)

Coomes SM, Kannan Y, Pelly VS, Entwistle LJ, Guidi R, Perez-Lloret J, Nikolov N, Müller W, Wilson MS. CD4+ Th2 cells are directly regulated by IL-10 during allergic airway inflammation. Mucosal Immunol. 2016 May 11. (11B11, FC, PubMed)

Lee JK, Kannarkat GT, Chung J, Joon Lee H, Graham KL, Tansey MG. RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2016 Feb 1;13:24. (11B11, FA, PubMed)

Abrams, J. 1995. Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies. In Current Protocols in Immunology. A. Kruisbeek eds. Wiley-Interscience, New York. Unit 6.20.1.

Ohara, J. and W. E. Paul. 1985. Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1. Nature. 1985 May 23-29;315(6017):333-6.