Anti-Mouse IL-4 Functional Grade Purified

Also known as: Interleukin-4

Clone: 11B11

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 16-7041

Cat. No. Size
16-7041-81 50 ug
16-7041-85 500 ug
Please inquire about custom configurations or bulk packaging.

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Data for Anti-Mouse IL-4 Functional Grade Purified.

Splenocytes from 8 week old mice pre-immunized with OVA/IFA were recall-activated with OVA antigen...View More

  • Data for Anti-Mouse IL-4 Functional Grade Purified.
Description

Description: The 11B11 antibody reacts with mouse interleukin-4 (IL-4), a 14 kD cytokine. The 11B11 antibody is a neutralizing antibody. Mouse IL-4, also known as BCDF, BCGF-1 and BSF-1, is secreted by activated Th2 and natural killer T cells, and to a lesser extent by Th1 and mast cells. IL-4 is species-specific and promotes proliferation and differentiation of B cells. IL-4, in conjunction with other signals such as CD40, induces Ig isotype switching of B cells and the upregulation of surface MHC class II and CD23.

Details
Host Rat
Isotype IgG1, kappa
Reactivity Mouse
Reported Applications ELISA Capture Antibody, ELISPOT, Functional Assays
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
17-7041 Anti-Mouse IL-4 APC 633 - 647 nm 660 nm FC RUO
25-7041 Anti-Mouse IL-4 PE-Cyanine7 488 - 561 nm 775 nm FC RUO
14-7041 Anti-Mouse IL-4 Purified ELISA RUO
53-7041 Anti-Mouse IL-4 Alexa Fluor® 488 488 nm 519 nm FC RUO
12-7041 Anti-Mouse IL-4 PE 488 - 561 nm FC RUO
46-7041 Anti-Mouse IL-4 PerCP-eFluor® 710 488 nm 710 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
00-4201 1X TMB ELISA Substrate Solution ELISA RUO
14-8041 Mouse IL-4 Recombinant Protein ELISA, FA RUO
13-7042 Anti-Mouse IL-4 Biotin ELISA RUO
References

References: Abrams, J. 1995. Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies. In Current Protocols in Immunology. A. Kruisbeek eds. Wiley-Interscience, New York. Unit 6.20.1.

Ohara, J. and W. E. Paul. 1985. Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1. Nature. 1985 May 23-29;315(6017):333-6.