Anti-Mouse IL-4 Alexa Fluor® 488

Also known as: Interleukin-4

Clone: 11B11

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 53-7041

Cat. No.	Size
53-7041-80	25 ug
53-7041-82	100 ug
Please inquire about custom configurations or bulk packaging.

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Intracellular staining of Th2-polarized mouse splenocytes with Anti-Mouse CD4 APC-eFluor® 780 (cat....View More

Description

Description: The 11B11 antibody reacts with mouse interleukin-4 (IL-4), a 14 kD cytokine. The 11B11 antibody is a neutralizing antibody. Mouse IL-4, also known as BCDF, BCGF-1 and BSF-1, is secreted by activated Th2 and natural killer T cells, and to a lesser extent by Th1 and mast cells. IL-4 is species-specific and promotes proliferation and differentiation of B cells. IL-4, in conjunction with other signals such as CD40, induces Ig isotype switching of B cells and the upregulation of surface MHC class II and CD23.

Details

Host	Rat
Isotype	IgG1, kappa
Reactivity	Mouse
Conjugate	Alexa Fluor 488
Laser	Blue Laser
Emit	519 nm
Excite	488 nm
Legal	Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications	Intracellular Staining Followed by Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
17-7041	Anti-Mouse IL-4 APC	633 - 647 nm	660 nm	FC	RUO
12-7041	Anti-Mouse IL-4 PE	488 - 561 nm		FC	RUO
14-7041	Anti-Mouse IL-4 Purified			ELISA	RUO
46-7041	Anti-Mouse IL-4 PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
16-7041	Anti-Mouse IL-4 Functional Grade Purified			ELISA, FA	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
00-4975	Cell Stimulation Cocktail (plus protein transport inhibitors) (500X)			FC, FA	GPR
16-0031	Anti-Mouse CD3e Functional Grade Purified			FC, FA	RUO
16-0281	Anti-Mouse CD28 Functional Grade Purified			FC, FA	RUO
53-4301	Rat IgG1 K Isotype Control Alexa Fluor® 488	488 nm	519 nm	FC, ICC, IHC	RUO
65-0863	Fixable Viability Dye eFluor® 450			FC	GPR
47-0041	Anti-Mouse CD4 APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
88-8824	Intracellular Fixation & Permeabilization Buffer Set			FC	GPR

References

References: Abrams, J. 1995. Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies. In Current Protocols in Immunology. A. Kruisbeek eds. Wiley-Interscience, New York. Unit 6.20.1.

Ohara, J. and W. E. Paul. 1985. Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1. Nature. 1985 May 23-29;315(6017):333-6.

View More Products

Antigens	Area of Biology	Cell Type	Formats
IL-4	Adaptive Immunity Cytokines, Chemokines, Growth Factors Innate Immunity	T Cells Th2 Cells	Alexa Fluor 488