Mouse IL-1alpha Platinum ELISA

Also known as: Hematopoietin 1, IL1F1, Interleukin 1 alpha

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# BMS611*

Cat. No. Size
BMS611 96 tests
BMS611TEN 10 x 96 tests
Please inquire about custom configurations or bulk packaging.

To enable ordering, please select your country. Cookies will need to be enabled to continue on our website. View our Privacy Policy.

Data for Mouse IL-1alpha Platinum ELISA.

Click on image to view more information.

  • Data for Mouse IL-1alpha Platinum ELISA.
Description

Description: The mouse IL-1alpha ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of mouse IL-1alpha. The mouse IL-1alpha ELISA is for research use only. Not for diagnostic or therapeutic procedures.

The interleukin-1 species represent an important family of biologically active mono nuclear cell-derived proteins which are involved in inflammatory reactions and in immune responses. Two distinct IL-1 species, IL-1alpha and IL-1beta, have been identified. They share similarities such as the same molecular weight, similar biological effects and the same receptors on target cells. IL-1 proteins are produced by macrophages, monocytes and various other cell types such as adult T cell leukemias, fibroblasts, epithelial or endothelial cells, neutrophils and astrocytes. Their biological properties include pyrogenicity, bone resorption, presentation of antigen to T cells and stimulation of B and T lymphocyte proliferation.

Details
Reactivity Mouse
Sample Volume 50 uL
Suitable Sample Types cell culture supernatant, serum
Sensitivity 4.0 pg/mL
Standard Curve Range 7.8 - 500 pg/mL
Components Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to mouse IL-1alpha
Biotin-Conjugate anti-mouse IL-1alpha monoclonal antibody
Streptavidin-HRP
Mouse IL-1alpha Standard lyophilized, 1000 pg/ml upon reconstitution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films
Reported Applications ELISA
Documentation
TDS Link Download TDS
Related Products
Cat. No. Name Excite Emit Application Reg.
14-8011 Mouse IL-1 alpha Recombinant Protein ELISA RUO
BMS6002INST* Mouse IL-1beta Instant ELISA ELISA RUO
BMS603/2* Mouse IL-6 Platinum ELISA ELISA RUO
BMS8607/2FF* Mouse TNF-alpha FlowCytomix Simplex Multiplex RUO
References

References: Astiz,M.E.; Saha,D.C.; Carpati,C.M.; Rackow,E.C.. Induction of endotoxin tolerance with monophosphoryl lipid A in peritonitis: importance of localized therapy. J.Lab Clin.Med. 1994;123:89-93. (Link)

Lee,S.H.; Brennan,F.R.; Jacobs,J.J.; Urban,R.M.; Ragasa,D.R.; Glant,T.T.. Human monocyte/macrophage response to cobalt-chromium corrosion products and titanium particles in patients with total joint replacements. J.Orthop.Res. 1997;15:40-49. (Link)

Yamashita,U.; Shirakawa,F.; Nakamura,H.. Production of interleukin 1 by adult T cell leukemia (ATL) cell lines. J.Immunol. 1987;138:3284-3289. (Link)

Basso,D.; Plebani,M.; Fogar,P.; Panozzo,M.P.; Meggiato,T.; De,Paoli M.; Del,Favero G.. Insulin-like growth factor-I, interleukin-1 alpha and beta in pancreatic cancer: role in tumor invasiveness and associated diabetes. Int J.Clin.Lab Res. 1995;25:40-43. (Link)

Mantovani,G.; Maccio,A.; Bianchi,A.; Curreli,L.; Ghiani,M.; Santona,M.C.; Del Giacco,G.S.. Megestrol acetate in neoplastic anorexia/cachexia: clinical evaluation and comparison with cytokine levels in patients with head and neck carcinoma treated with neoadjuvant chemotherapy. Int J.Clin.Lab Res. 1995;25:135-141. (Link)

Wilmott,R.W.; Frenzke,M.; Kociela,V.; Peng,L.. Plasma interleukin-1 alpha and beta, tumor necrosis factor-alpha, and lipopolysaccharide concentrations during pulmonary exacerbations of cystic fibrosis. Pediatr.Pulmonol. 1994;18:21-27. (Link)

Jurincic-Winkler,C.D.; Gallati,H.; varez-Mon,M.; Sippel,J.; Carballido,J.; Klippel,K.F.. Urinary interleukin-1 alpha levels are increased by intravesical instillation with keyhole limpet hemocyanin in patients with superficial transitional cell carcinoma of the bladder. Eur.Urol. 1995;28:334-339. (Link)

Shanbhag,A.S.; Jacobs,J.J.; Black,J.; Galante,J.O.; Glant,T.T.. Cellular mediators secreted by interfacial membranes obtained at revision total hip arthroplasty. J.Arthroplasty 1995;10:498-506. (Link)

Mizel,S.B.. Interleukin 1 and T cell activation. Immunol.Rev. 1982;63:51-72. (Link)

Yoshida,A.; Asaga,T.; Masuzawa,C.; Kawahara,S.; Yanoma,S.; Harada,M.; Okamoto,T.. Production of cytokines by thyroid carcinoma cell lines. J.Surg.Oncol. 1994;55:104-107. (Link)

Schuster,A.; Haarmann,A.; Wahn,V.. Cytokines in neutrophil-dominated airway inflammation in patients with cystic fibrosis. Eur.Arch.Otorhinolaryngol. 1995;252 Suppl :S59-S60. (Link)

Wood,D.D.; Bayne,E.K.; Goldring,M.B.; Gowen,M.; Hamerman,D.; Humes,J.L.; Ihrie,E.J.; Lipsky,P.E.; Staruch,M.J.. The four biochemically distinct species of human interleukin 1 all exhibit similar biologic activities. J.Immunol. 1985;134:895-903. (Link)