Anti-Mouse IL-10 PerCP-Cy5.5

Also known as: Interleukin-10, IL10

Clone: JES5-16E3

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 45-7101

Cat. No. Size
45-7101-80 25 ug
45-7101-82 100 ug

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Data for Anti-Mouse IL-10 PerCP-Cy5.5.

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  • Data for Anti-Mouse IL-10 PerCP-Cy5.5.
Description

Description: The JES5-16E3 antibody reacts with mouse interleukin-10 (IL-10). Mouse IL-10 is an ~18 kDa factor also known as Cytokine Synthesis Inhibitory Factor (CSIF). In the mouse, Th2 cells, B1 cells, macrophages, and keratinocytes are the major cell subsets that produce IL-10. IL-10 inhibits synthesis of Th1 cytokines and proliferation of T cells, and acts as a costimulatory signal for mast cells, developing thymocytes and the Th2 response.

Details
Host Rat
Isotype IgG2b, kappa
Reactivity Mouse
Conjugate PerCP-Cy5.5
Laser Blue Laser
Emit 690 nm
Excite 488 nm
Legal FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
17-7101 Anti-Mouse IL-10 APC 633 nm 660 nm FC RUO
53-7101 Anti-Mouse IL-10 Alexa Fluor® 488 488 nm 519 nm FC RUO
51-7101 Anti-Mouse IL-10 Alexa Fluor® 647 (Discontinued. Refer to Alternative Format: APC cat. 17-7101) 633 nm 668 nm FC RUO
56-7101 Anti-Mouse IL-10 Alexa Fluor® 700 633 nm 723 nm FC RUO
14-7101 Anti-Mouse IL-10 Purified ELISA RUO
36-7101 Anti-Mouse IL-10 Functional Grade Biotin FA RUO
16-7101 Anti-Mouse IL-10 Functional Grade Purified ELISA, FA RUO
11-7101 Anti-Mouse IL-10 FITC 488 nm 518 nm FC RUO
12-7101 Anti-Mouse IL-10 PE 488 nm 575 nm FC RUO
References

References: Sander, B., I. Hoiden, et al. 1993. Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining. J Immunol Meth. 1662: 201-14.
Abrams, J. 1995. Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies. In Current Protocols in Immunology. A. Kruisbeek eds. Wiley-Interscience, New York. Unit 6.20.1.
Finkelman, F., S. Morris, T. Orekhova, and D. Sehy. 2003. The In Vivo Cytokine Capture Assay for measurement of cytokine production in the mouse. In Current Protocols in Immunology. Unit 6.28. J. Coligan, A. Kruisbeek, D. Margulies, E. Shevach, and W. Strober, eds. John Wiley and Sons, New York.
Finkelman, F.D., and S.C. Morris. 1999. Development of an assay to measure in vivo cytokine production in the mouse. Int. Immunology. 11: 1811-1818.