Anti-Mouse IFN gamma Functional Grade Purified

Also known as: Interferon gamma, IFNG

Clone: H22

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 16-7411

Cat. No. Size
16-7411-81 50 ug
16-7411-85 500 ug
Please inquire about custom configurations or bulk packaging.

To enable ordering, please select your country. Cookies will need to be enabled to continue on our website. View our Privacy Policy.

Data for Anti-Mouse IFN gamma Functional Grade Purified.

Description

Description: This H22 monoclonal antibody reacts with and inhibits the activity of Mouse IFN gamma. Mouse IFN gamma is a 20 kDa factor produced by activated T, B, and NK cells, and is an anti-viral and anti-parasitic cytokine. IFN gamma, in synergy with other cytokines such as TNF alpha, inhibits proliferation of normal and transformed cells. Immunomodulatory effects of IFN gamma are exerted on a wide range of cell types expressing the high affinity receptors for IFN gamma.

Details
Host Armenian Hamster
Isotype IgG
Reactivity Mouse
Conjugate Functional Grade Purified (low endotoxin, azide-free)
Reported Applications Functional Assays, Cytokine Bioassays
Documentation
TDS Link Download TDS
Related Products
Cat. No. Name Excite Emit Application Reg.
14-8311 Mouse IFN gamma Recombinant Protein FA RUO
16-4888 Armenian Hamster IgG Isotype Control Functional Grade Purified FC RUO
References

References: Zhang Y, Xu G, Zhang L, Roberts AI, Shi Y. Th17 cells undergo Fas-mediated activation-induced cell death independent of IFN-gamma. J Immunol. 2008 Jul 1;181(1):190-6.

Cho KS, Hill AB. T cell acquisition of APC membrane can impact interpretation of adoptive transfer experiments using CD45 congenic mouse strains. J Immunol Methods. 2008 Jan 31;330(1-2):137-45.

Kimura A, Naka T, Kishimoto T. IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12099-104.

Feng X, Akiyoshi DE, Sheoran A, Singh I, Hanawalt J, Zhang Q, Widmer G, Tzipori S. Serial propagation of the microsporidian Enterocytozoon bieneusi of human origin in immunocompromised rodents. Infect Immun. 2006 Aug;74(8):4424-9.

Hidalgo LG, Urmson J, Halloran PF. IFN-gamma decreases CTL generation by limiting IL-2 production: A feedback loop controlling effector cell production. Am J Transplant. 2005 Apr;5(4 Pt 1):651-61.

Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol Rev. 1992 Jun;127:5-24.