Anti-Mouse GITR Ligand PE

Also known as: GITRL, GITR-L, AITR Ligand, AITRL, AITR-L, TNFSF18

Clone: eBioYGL386 (YGL 386, YGL-386)

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 12-5854

Cat. No.	Size
12-5854-80	25 ug
12-5854-82	100 ug
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Staining of mouse thioglycolate-induced peritoneal exudate cells with 0.5 ug of Rat IgG1 kappa...View More

Description

Description: The eBioYGL386 monoclonal antibody reacts with mouse GITR Ligand, also known as TL6. GITRL is a type II transmembrane protein of the TNF superfamily and is expressed by endothelial cells and peripheral blood monocytes. Interaction of GITR, expressed by CD4+CD25+ Regulatory T cells, with GITRL is important for cross-talk between T lymphocytes and endothelial cells.

Details

Host	Rat
Isotype	IgG1
Reactivity	Mouse
Conjugate	PE
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Emit	575 nm
Excite	488 - 561 nm
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
12-4301	Rat IgG1 K Isotype Control PE	488 - 561 nm		FC	RUO

References

References: Tone, M., Y. Tone, E. Adams, S.F. Yates, M.R. Frewin, S.P. Cobbold and H. Waldmann. 2003. Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells. Proc. Natl. Acad. Sci. USA. 100: 15059-15064. (eBioYGL386, FC, PubMed)

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Antigens	Area of Biology	Cell Type	Formats
GITR Ligand	Innate Immunity	Dendritic Cells Macrophage & Monocyte Cells T Cells Treg Cells	PE