Anti-Mouse CXCL9 (MIG) Alexa Fluor 647 (Discontinued. Refer to Cat. No. 50-3009)

Also known as: monokine induced by IFN-g

Clone: MIG-2F5.5

RUO: For Research Use Only. Not for use in diagnostic procedures.

Attention: Alternative format is eFluor 660. Select Cat. No. 50-3009

SKU# 51-3009

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Intracellular staining of LPS-stimulated (left) and IFN gamma stimulated (right) BALB/c...View More

Description

Description: The monoclonal antibody MIG-2F5.5 reacts with mouse monokine induced by IFN gamma (mig, mig-1, CXCL9). This 14.4 kDa inflammatory chemokine is specifically induced by IFN gamma, but not other activators such as LPS or IFN alpha. Secretion of mig, mainly by macrophages results in the chemotaxis of a variety of activated T cells via the CXCR3 chemokine receptor. Mig is involved many areas of research including autoimmune diseases, cancer, and inflammation.

Details

Host	Armenian Hamster
Isotype	IgG
Reactivity	Mouse
Conjugate	Alexa Fluor 647
Laser	Red Laser
Emit	668 nm
Excite	633 - 647 nm
Legal	Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications	Intracellular Staining Followed by Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
50-3009	Anti-Mouse CXCL9 (MIG) eFluor® 660 (Alexa Fluor® 647 Replacement)	633 nm	668 nm	FC	RUO
12-3009	Anti-Mouse CXCL9 (MIG) PE	488 - 561 nm	575 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
12-0112	Anti-Mouse CD11b PE	488 - 561 nm	575 nm	FC	RUO
14-8311	Mouse IFN gamma Recombinant Protein			FA	RUO
51-4888	Armenian Hamster IgG Isotype Control Alexa Fluor® 647 (To Be Discontinued. Refer to Cat. No. 50-4888)	633 - 647 nm	668 nm	FC, ICC, IHC	RUO

References

References: Lu H, Yu M, Sun Y, Mao W, Wang Q, Wu M, Han W. Expression and purification of bioactive high-purity mouse monokine induced by IFN-gamma in Escherichia coli.Protein Expr Purif. 2007 Sep;55(1):132-8.

Klunker S, Trautmann A, Akdis M, Verhagen J, Schmid-Grendelmeier P, Blaser K, Akdis CA. A Second Step of Chemotaxis After Transendothelial Migration: Keratinocytes Undergoing Apoptosis Release IFN-gamma-Inducible Protein 10, Monokine Induced by IFN-gamma, and IFN-gamma-Inducible alpha-Chemoattractant for T Cell Chemotaxis Toward Epidermis in Atopic Dermatitis. J Immunol. 2003 Jul 15;171(2):1078-84.

Liao F, Rabin RL, Yannelli JR, Koniaris LG, Vanguri P, Farber JM. Human Mig chemokine: biochemical and functional characterization. J Exp Med. 1995 Nov 1;182(5):1301-14.

Wong P, Severns CW, Guyer NB, Wright TM. A unique palindromic element mediates gamma interferon induction of mig gene expression. Mol Cell Biol. 1994 Feb;14(2):914-22.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CXCL9 (MIG)	Adhesion & Migration Cytokines, Chemokines, Growth Factors	Macrophage & Monocyte Cells T Cells	Alexa Fluor 647