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Anti-Mouse CD62L (L-Selectin) Super Bright 600

Also known as: LECAM-1, Ly-22

Clone: MEL-14

RUO: For Research Use Only. Not for use in diagnostic procedures.

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SKU# 63-0621

Cat. No. Size
63-0621-80 25 ug
63-0621-82 100 ug

Data for Anti-Mouse CD62L (L-Selectin) Super Bright 600.

Staining of C57Bl/6 splenocytes with Anti-Mouse CD3e FITC (cat. 11-0031) and 0.06 ug of Rat IgG2a K...View More

  • Data for Anti-Mouse CD62L (L-Selectin) Super Bright 600.
Description

Description: The MEL-14 monoclonal antibody reacts with mouse CD62L, a 76 kDa member of the selectin family. CD62L is expressed by neutrophils, monocytes, and subsets of T, B, and NK cells and binds a number of glycosylated, fucosylated, sulfated sialylated glycoproteins including CD34, glycam-1 and MAdCam-1. These interactions mediate rolling of lymphocytes on activated endothelium at the sites of inflammation and homing of cells to the high endothelial venules (HEV) of peripheral lymphoid tissues.

Details
Host Rat
Isotype IgG2a, kappa
Reactivity Mouse
Conjugate Super Bright 600
Laser Violet Laser
Emit 600 nm
Excite 405 nm
Legal Patent pending.
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
15-0621 Anti-Mouse CD62L (L-Selectin) PE-Cyanine5 488 - 561 nm 667 nm FC RUO
48-0621 Anti-Mouse CD62L (L-Selectin) eFluor® 450 405 nm 445 nm FC RUO
16-0621 Anti-Mouse CD62L (L-Selectin) Functional Grade Purified FC, FA RUO
45-0621 Anti-Mouse CD62L (L-Selectin) PerCP-Cyanine5.5 488 nm 695 nm FC RUO
11-0621 Anti-Mouse CD62L (L-Selectin) FITC 488 nm 520 nm FC RUO
13-0621 Anti-Mouse CD62L (L-Selectin) Biotin FC RUO
25-0621 Anti-Mouse CD62L (L-Selectin) PE-Cyanine7 488 - 561 nm 775 nm FC RUO
12-0621 Anti-Mouse CD62L (L-Selectin) PE 488 - 561 nm 578 nm FC RUO
56-0621 Anti-Mouse CD62L (L-Selectin) Alexa Fluor® 700 633 - 647 nm 723 nm FC RUO
83-0621 Anti-Mouse CD62L (L-Selectin) eVolve™ 605 605 nm FC RUO
47-0621 Anti-Mouse CD62L (L-Selectin) APC-eFluor® 780 633 - 647 nm 780 nm FC RUO
17-0621 Anti-Mouse CD62L (L-Selectin) APC 633 - 647 nm 660 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
11-0031 Anti-Mouse CD3e FITC 488 nm 520 nm FC, IHC, IHC-F RUO
SB-4400 Super Bright Staining Buffer FC GPR
63-4321 Rat IgG2a K Isotype Control Super Bright 600 405 nm 600 nm FC RUO
References

References: Gallatin, W. M., I. L. Weissman, et al. (1983). A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature 304(5921): 30-4.

Siegelman, M. H., I. C. Cheng, et al. (1990). The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: role of the EGF domain in endothelial binding. Cell 61(4): 611-22.