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Anti-Mouse CD49d (Integrin alpha 4) PE

Also known as: Integrin a4, VLA4, ITGA4

Clone: R1-2

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 12-0492

Cat. No. Size
12-0492-81 50 ug
12-0492-82 100 ug
12-0492-83 200 ug
Please inquire about custom configurations or bulk packaging.

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Data for Anti-Mouse CD49d (Integrin alpha 4) PE.

Staining of BALB/c splenocytes with 0.5 ug of Rat IgG2b K Isotype Control PE (cat. 12-4031) (blue...View More

  • Data for Anti-Mouse CD49d (Integrin alpha 4) PE.
Description

Description: The R1-2 monoclonal antibody reacts with mouse CD49d, the 150 kDa integrin alpha4 subunit. The complex of CD49d non-covalently associated with integrin beta1 (CD29), also known as VLA-4, is a receptor for fibronectin and VCAM-1 (CD106). This complex is expressed by thymocytes, peripheral lymphocytes, monocytes and eosinophils. CD49d also associates with integrin b7 and binds to the Mucosal vascular Addressin (MAdCAM-1).

Details
Host Rat
Isotype IgG2b, kappa
Reactivity Mouse
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
46-0492 Anti-Mouse CD49d (Integrin alpha 4) PerCP-eFluor® 710 488 nm 710 nm FC RUO
16-0492 Anti-Mouse CD49d (Integrin alpha 4) Functional Grade Purified FC RUO
11-0492 Anti-Mouse CD49d (Integrin alpha 4) FITC 488 nm 518 nm FC RUO
13-0492 Anti-Mouse CD49d (Integrin alpha 4) Biotin FC RUO
14-0492 Anti-Mouse CD49d (Integrin alpha 4) Purified FC, IHC, FA, IP RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
12-4031 Rat IgG2b K Isotype Control PE 488 - 561 nm FC RUO
References

References: Holzmann B, McIntyre BW, Weissman IL. Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha. Cell. 1989 Jan 13;56(1):37-4.

Neuhaus H, Hu MC, Hemler ME, Takada Y, Holzmann B, Weissman IL. Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule. J Cell Biol. 1991 Nov;115(4):1149-58.

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