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Anti-Mouse CD49d (Integrin alpha 4) FITC

Also known as: Integrin a4, VLA4, ITGA4

Clone: R1-2

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 11-0492

Cat. No. Size
11-0492-81 50 ug
11-0492-82 100 ug
11-0492-85 500 ug
Please inquire about custom configurations or bulk packaging.

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Data for Anti-Mouse CD49d (Integrin alpha 4) FITC.

Staining of BALB/c splenocytes with 0.25 ug of Rat IgG2b K Isotype Control FITC (cat. 11-4031) (blue...View More

  • Data for Anti-Mouse CD49d (Integrin alpha 4) FITC.
Description

Description: The R1-2 monoclonal antibody reacts with mouse CD49d, the 150 kDa integrin alpha4 subunit. The complex of CD49d non-covalently associated with integrin beta1 (CD29), also known as VLA-4, is a receptor for fibronectin and VCAM-1 (CD106). This complex is expressed by thymocytes, peripheral lymphocytes, monocytes and eosinophils. CD49d also associates with integrin b7 and binds to the Mucosal vascular Addressin (MAdCAM-1).

Details
Host Rat
Isotype IgG2b, kappa
Reactivity Mouse
Conjugate FITC
Laser Blue Laser
Emit 518 nm
Excite 488 nm
Reported Applications Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
16-0492 Anti-Mouse CD49d (Integrin alpha 4) Functional Grade Purified FC RUO
12-0492 Anti-Mouse CD49d (Integrin alpha 4) PE 488 - 561 nm 575 nm FC RUO
46-0492 Anti-Mouse CD49d (Integrin alpha 4) PerCP-eFluor® 710 488 nm 710 nm FC RUO
13-0492 Anti-Mouse CD49d (Integrin alpha 4) Biotin FC RUO
14-0492 Anti-Mouse CD49d (Integrin alpha 4) Purified FC, IHC, FA, IP RUO
References

References: Holzmann B, McIntyre BW, Weissman IL. Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha. Cell. 1989 Jan 13;56(1):37-4.

Neuhaus H, Hu MC, Hemler ME, Takada Y, Holzmann B, Weissman IL. Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule. J Cell Biol. 1991 Nov;115(4):1149-58.

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