Anti-Mouse CD49b (Integrin alpha 2) Functional Grade Purified

Also known as: Integrin a2, VLA2, ITGA2, DX5

Clone: HMa2

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 16-0491

Cat. No. Size
16-0491-81 50 ug
16-0491-85 500 ug
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Data for Anti-Mouse CD49b (Integrin alpha 2) Functional Grade Purified.

Staining of mouse splenocytes with Anti-Mouse CD49b (Integrin alpha 2) FITC. Appropriate isotype...View More

  • Data for Anti-Mouse CD49b (Integrin alpha 2) Functional Grade Purified.
Description

Description: The HMα2 monoclonal antibody reacts with mouse CD49b, the 150 kDa integrin α2 subunit. The complex of CD49b non-covalently associated with integrin β1 (CD29), also known as VLA-2, is a receptor for collagen and laminin. This complex is expressed by some CD4+ T cells, IEL, NK cells, platelets and epithelial cells.

Details
Host Armenian Hamster
Isotype IgG
Reactivity Mouse
Conjugate Functional Grade Purified (low endotoxin, azide-free)
Reported Applications Flow Cytometric Analysis, Functional Assays
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
14-0491 Anti-Mouse CD49b (Integrin alpha 2) Purified FC, IHC, FA, IP RUO
13-0491 Anti-Mouse CD49b (Integrin alpha 2) Biotin FC RUO
11-0491 Anti-Mouse CD49b (Integrin alpha 2) FITC 488 nm 518 nm FC RUO
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References

References:
Miyake, S., T. Sakurai, et al. (1994). "Identification of collagen and laminin receptor integrins on murine T lymphocytes." Eur J Immunol 24(9): 2000-5.
Noto, K., K. Kato, et al. (1995). "Identification and functional characterization of mouse CD29 with a mAb." Int Immunol 7(5): 835-42.