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Staining of mouse splenocytes with Anti-Mouse CD45RC FITC (left) and PE (right). Appropriate...View More
Description: The GL24 monoclonal antibody reacts with the exon C-dependent isoform of mouse CD45. This CD45 isoform is expressed by peripheral B cells and a population of CD4+ T cells at high levels, on a majority of CD8+ T cells at intermediate levels and by a subpopulation of mouse thymocytes. CD45 is a protein tyrosine phosphatase and serves an important role in leukocyte signal transduction.
References: Hathcock, K. S., G. Laszlo, et al. (1992).Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations. J Immunol 148(1): 19-28.
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