Anti-Mouse CD45RB Biotin

Description: The C363.16A monoclonal antibody reacts with the exon B-dependent isoform of mouse CD45. This CD45 isoform is expressed by thymocytes, peripheral B cells and a subpopulation of T cells at high density and by dendritic cells and macrophages at low density. CD45 is a protein tyrosine phosphatase and serves an important role in leukocyte signal transduction.

References:
Bottomly, K., M. Luqman, et al. (1989). "A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines." Eur J Immunol 19(4): 617-23.
Johnson, P., L. Greenbaum, et al. (1989). "Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies." J Exp Med 169(3): 1179-84.