Anti-Mouse CD45RB APC

Clone: C363.16A

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 17-0455

Cat. No.	Size
17-0455-81	50 ug
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Staining of C57BL/6 splenocytes with 0.125 ug of Rat IgG2a kappa Isotype Control APC (cat. 17-4321)...View More

Description

Description: The C363.16A monoclonal antibody reacts with the exon B-dependent isoform of mouse CD45. This CD45 isoform is expressed by thymocytes, peripheral B cells and a subpopulation of T cells at high density and by dendritic cells and macrophages at low density. CD45 is a protein tyrosine phosphatase and serves an important role in leukocyte signal transduction.

Details

Host	Rat
Isotype	IgG2a, kappa
Reactivity	Mouse
Conjugate	APC
Laser	Red Laser
Emit	660 nm
Excite	633 - 647 nm
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
11-0455	Anti-Mouse CD45RB FITC	488 nm	518 nm	FC	RUO
12-0455	Anti-Mouse CD45RB PE	488 - 561 nm	575 nm	FC	RUO
13-0455	Anti-Mouse CD45RB Biotin			FC	RUO
14-0455	Anti-Mouse CD45RB Purified			FC, IHC, IP	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
17-4321	Rat IgG2a K Isotype Control APC	633 - 647 nm	660 nm	FC	RUO

References

References:
Bottomly, K., M. Luqman, et al. (1989). "A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines." Eur J Immunol 19(4): 617-23.
Johnson, P., L. Greenbaum, et al. (1989). "Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies." J Exp Med 169(3): 1179-84.

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Antigens	Area of Biology	Cell Type	Formats
CD45RB	Adaptive Immunity Cell Signaling	B Cells Dendritic Cells Macrophage & Monocyte Cells T Cells	APC