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Anti-Mouse CD4 Super Bright 600

Also known as: L3T4, Ly-4

Clone: RM4-5

RUO: For Research Use Only. Not for use in diagnostic procedures.

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SKU# 63-0042

Cat. No. Size
63-0042-80 25 ug
63-0042-82 100 ug

Data for Anti-Mouse CD4 Super Bright 600.

Staining of C57Bl/6 splenocytes with Anti-Mouse CD3 APC (cat. 17-0032) and 0.06 ug of Rat IgG2a K...View More

  • Data for Anti-Mouse CD4 Super Bright 600.
Description

Description: The RM4-5 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells and dendritic cells. CD4 binds to MHC class II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal functioning of mature T cells. In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail. Binding of RM4-5 is blocked by GK1.5.

Details
Host Rat
Isotype IgG2a, kappa
Reactivity Mouse
Conjugate Super Bright 600
Laser Violet Laser
Emit 600 nm
Excite 405 nm
Legal Patent pending.
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
11-0042 Anti-Mouse CD4 FITC 488 nm 520 nm FC RUO
25-0042 Anti-Mouse CD4 PE-Cyanine7 488 - 561 nm 775 nm FC RUO
17-0042 Anti-Mouse CD4 APC 633 - 647 nm 660 nm FC RUO
58-0042 Anti-Mouse CD4 Alexa Fluor® 532 532 nm 561 nm FC RUO
69-0042 Anti-Mouse CD4 eFluor® 506 405 nm 506 nm FC RUO
83-0042 Anti-Mouse CD4 eVolve™ 605 605 nm FC RUO
48-0042 Anti-Mouse CD4 eFluor® 450 405 nm 445 nm FC RUO
13-0042 Anti-Mouse CD4 Biotin FC RUO
42-0042 Anti-Mouse CD4 eFluor® 615 595 nm 615 nm ICC, IHC, IHC-F RUO
47-0042 Anti-Mouse CD4 APC-eFluor® 780 633 - 647 nm 780 nm FC RUO
56-0042 Anti-Mouse CD4 Alexa Fluor® 700 633 - 647 nm 723 nm FC RUO
61-0042 Anti-Mouse CD4 PE-eFluor® 610 488 - 561 nm 607 nm FC RUO
41-0042 Anti-Mouse CD4 eFluor® 570 555 nm 570 nm ICC, IHC, IHC-F RUO
15-0042 Anti-Mouse CD4 PE-Cyanine5 488 - 561 nm 667 nm FC RUO
35-0042 Anti-Mouse CD4 PE-Cyanine5.5 488 - 567 nm 690 nm FC RUO
46-0042 Anti-Mouse CD4 PerCP-eFluor® 710 488 nm 710 nm FC RUO
12-0042 Anti-Mouse CD4 PE 488 - 561 nm 578 nm FC RUO
14-0042 Anti-Mouse CD4 Purified FC, IHC, IHC-F, FA RUO
45-0042 Anti-Mouse CD4 PerCP-Cyanine5.5 488 nm 695 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
63-4321 Rat IgG2a K Isotype Control Super Bright 600 405 nm 600 nm FC RUO
17-0032 Anti-Mouse CD3 APC 633 - 647 nm 660 nm FC RUO
SB-4400 Super Bright Staining Buffer FC GPR
References

References: Irie J, Wu Y, Wicker LS, Rainbow D, Nalesnik MA, Hirsch R, Peterson LB, Leung PS, Cheng C, Mackay IR, Gershwin ME, Ridgway WM. NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis. J Exp Med. 2006 May 15;203(5):1209-19. (RM4-5, IHC frozen)

Andres PG, Beck PL, Mizoguchi E, Mizoguchi A, Bhan AK, Dawson T, Kuziel WA, Maeda N, MacDermott RP, Podolsky DK, Reinecker HC. Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine. J Immunol. 2000 Jun 15;164(12):6303-12. (RM4-5, IHC frozen)


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