Anti-Mouse CD31 (PECAM-1) PE-Cy7

Also known as: Platelet-Endothelial Cell Adhesion Molecule 1

Clone: 390

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 25-0311

Cat. No.	Size
25-0311-81	50 ug
25-0311-82	100 ug

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Description

Description: The 390 monoclonal antibody reacts with mouse CD31, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) and gpIIa. This 130-140 kDa surface protein is expressed by endothelial cells and at low levels on all leukocytes and platelets. It has been reported that CD38 binds to CD31. Homotypic interaction of CD31 is important in adhesion, cell-cell and cell-matrix interaction, and signal transduction.

Details

Host	Rat
Isotype	IgG2a, kappa
Reactivity	Mouse
Conjugate	PE-Cy7
Laser	Blue Laser
Emit	760 nm
Excite	488 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

For complete product information, please download the TDS or IFU document.

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
48-0311	Anti-Mouse CD31 (PECAM-1) eFluor® 450	405 nm	450 nm	FC	RUO
12-0311	Anti-Mouse CD31 (PECAM-1) PE	488 nm	575 nm	FC	RUO
14-0311	Anti-Mouse CD31 (PECAM-1) Purified			FC, IHC, IP	RUO
46-0311	Anti-Mouse CD31 (PECAM-1) PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
13-0311	Anti-Mouse CD31 (PECAM-1) Biotin			FC	RUO
11-0311	Anti-Mouse CD31 (PECAM-1) FITC	488 nm	518 nm	FC	RUO
17-0311	Anti-Mouse CD31 (PECAM-1) APC	633 nm	660 nm	FC	RUO
IH93-0311	Anti-Mouse CD31 (PECAM-1) eFluor® 605NC (for IHC/ICC)	350 - 590 nm	605 nm	ICC, IHC	RUO
93-0311	Anti-Mouse CD31 (PECAM-1) eFluor® 605NC	350 - 590 nm	605 nm	FC	RUO
IH95-0311	Anti-Mouse CD31 (PECAM-1) eFluor® 650NC (for IHC/ICC)	350 - 635 nm	650 nm	ICC, IHC	RUO
16-0311	Anti-Mouse CD31 (PECAM-1) Functional Grade Purified			FC, FA	RUO

References

References: Sadri N, Schneider RJ. Auf1/Hnrnpd-Deficient Mice Develop Pruritic Inflammatory Skin Disease. J Invest Dermatol. 2009 Mar;129(3):657-70. (390, IHC frozen, PubMed)

Cao G, O'Brien CD, Zhou Z, Sanders SM, Greenbaum JN, Makrigiannakis A, DeLisser HM. Involvement of human PECAM-1 in angiogenesis and in vitro endothelial cell migration. Am J Physiol Cell Physiol. 2002 May;282(5):C1181-90. (390, IHC frozen)

Wiewrodt R, Anu P. Thomas, Luca Cipelletti, Melpo Christofidou-Solomidou, David A. Weitz, Sheldon I. Feinstein, David Schaffer, Steven M. Albelda, Michael Koval, and Vladimir R. Muzykantov. Size-dependent intracellular immunotargeting of therapeutic cargoes into endothelial cells.Blood. 2002 Feb 1;99(3):912-22.

Horenstein AL, Stockinger H, Imhof BA, Malavasi F. CD38 binding to human myeloid cells is mediated by mouse and human CD31. Biochem J. 1998 Mar 15;330 (Pt 3):1129-35.

Baldwin HS, Shen HM, Yan HC, DeLisser HM, Chung A, Mickanin C, Trask T, Kirschbaum NE, Newman PJ, Albelda SM, et al. Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development. 1994 Sep;120(9):2539-53.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD31 (PECAM-1)	Adhesion & Migration Cell Signaling Angiogenesis	B Cells Macrophage & Monocyte Cells NK & NKT Cells T Cells	PE-Cy7