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Anti-Mouse CD3 APC

Also known as: CD3 epsilon, CD3 e

Clone: 17A2

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 17-0032

Cat. No. Size
17-0032-80 25 ug
17-0032-82 100 ug

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Data for Anti-Mouse CD3e APC.

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  • Data for Anti-Mouse CD3e APC.
Description

Description: The 17A2 monoclonal antibody reacts with the mouse CD3 complex. CD3 subunits gamma, delta and epsilon are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 17A2 to CD3 initiates the intracellular biochemical pathway resulting in cellular activation and proliferation.

Details
Host Rat
Isotype IgG2b, kappa
Reactivity Mouse
Conjugate APC
Laser Red Laser
Emit 660 nm
Excite 633 nm
Reported Applications Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
50-0032 Anti-Mouse CD3 eFluor® 660 (Alexa Fluor® 647 Replacement) 633 nm 668 nm FC RUO
56-0032 Anti-Mouse CD3 Alexa Fluor® 700 633 nm 723 nm FC RUO
51-0032 Anti-Mouse CD3 Alexa Fluor® 647 (To Be Discontinued. Refer to Replacement Format eFluor® 660, cat. 50-0032) 633 nm 668 nm FC RUO
46-0032 Anti-Mouse CD3 PerCP-eFluor® 710 488 nm 710 nm FC RUO
48-0032 Anti-Mouse CD3 eFluor® 450 405 nm 450 nm FC RUO
16-0032 Anti-Mouse CD3 Functional Grade Purified FC, FA RUO
47-0032 Anti-Mouse CD3 APC-eFluor® 780 633 nm 780 nm FC RUO
14-0032 Anti-Mouse CD3 Purified FC, IHC, FA RUO
References

References: Zhang Y, McCormick LL, Desai SR, Wu C, Gilliam AC. Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation. J Immunol. 2002 Mar 15;168(6):3088-98.(17A2, IH/F, PubMed)

Miescher, G. C., M. Schreyer, et al. Production and characterization of a rat monoclonal antibody against the murine CD3 molecular complex. Immunol Lett. 1989: 23(2): 113-8.

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