Anti-Mouse CD3 Alexa Fluor® 700

Also known as: CD3 epsilon

Clone: 17A2

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 56-0032

Cat. No.	Size
56-0032-80	25 ug
56-0032-82	100 ug
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Staining of C57BL/6 splenocytes with Anti-Human/Mouse CD45R (B220) FITC (cat. 11-0452) and staining...View More

Description

Description: The 17A2 monoclonal antibody reacts with the mouse CD3 complex. CD3 subunits gamma, delta and epsilon are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 17A2 to CD3 initiates the intracellular biochemical pathway resulting in cellular activation and proliferation.

Details

Host	Rat
Isotype	IgG2b, kappa
Reactivity	Mouse
Conjugate	Alexa Fluor 700
Laser	Red Laser
Emit	723 nm
Excite	633 nm
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
47-0032	Anti-Mouse CD3 APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
11-0032	Anti-Mouse CD3 FITC	488 nm		FC	RUO
16-0032	Anti-Mouse CD3 Functional Grade Purified			FC, FA	RUO
17-0032	Anti-Mouse CD3 APC	633 - 647 nm	660 nm	FC	RUO
50-0032	Anti-Mouse CD3 eFluor® 660 (Alexa Fluor® 647 Replacement)	633 nm	668 nm	FC	RUO
46-0032	Anti-Mouse CD3 PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
48-0032	Anti-Mouse CD3 eFluor® 450	405 nm	450 nm	FC	RUO
58-0032	Anti-Mouse CD3 Alexa Fluor® 532	532 nm	561 nm	FC	RUO
14-0032	Anti-Mouse CD3 Purified			FC, IHC, FA	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
11-0452	Anti-Human/Mouse CD45R (B220) FITC	488 nm		FC	RUO
56-4031	Rat IgG2b K Isotype Control Alexa Fluor® 700	633 - 647 nm	723 nm	FC	RUO

References

References: Zhang Y, McCormick LL, Desai SR, Wu C, Gilliam AC. Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation. J Immunol. 2002 Mar 15;168(6):3088-98.(17A2, IH/F, PubMed)

Miescher, G. C., M. Schreyer, et al. Production and characterization of a rat monoclonal antibody against the murine CD3 molecular complex. Immunol Lett. 1989: 23(2): 113-8.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD3	Adaptive Immunity Cell Signaling	NK & NKT Cells T Cells Th17 Cells Treg Cells	Alexa Fluor 700