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  • Anti-Mouse CD3 Alexa Fluor® 647 (To Be Discontinued. Refer to Replacement Format eFluor® 660, cat. 50-0032)

Anti-Mouse CD3 Alexa Fluor® 647 (To Be Discontinued. Refer to Replacement Format eFluor® 660, cat. 50-0032)

Also known as: CD3 epsilon

Clone: 17A2

RUO: For Research Use Only. Not for use in diagnostic procedures.

Attention: To Be Discontinued. Refer to Anti-Mouse CD3 eFluor 660®, cat. 50-0032

SKU# 51-0032

Cat. No. Size
51-0032-80 25 ug
51-0032-82 100 ug

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Data for Anti-Mouse CD3 Alexa Fluor® 647 (To Be Discontinued. Refer to NEW Anti-Mouse CD3 eFluor® 660, cat. 50-0032).

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  • Data for Anti-Mouse CD3 Alexa Fluor® 647 (To Be Discontinued. Refer to NEW Anti-Mouse CD3 eFluor® 660, cat. 50-0032).
Description

Description: The 17A2 monoclonal antibody reacts with the mouse CD3 complex. CD3 subunits γ, δ and ε are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 17A2 to CD3 initiates the intracellular biochemical pathway resulting in cellular activation and proliferation.

Details
Host Rat
Isotype IgG2b, kappa
Reactivity Mouse
Conjugate Alexa Fluor 647
Laser Red Laser
Emit 668 nm
Excite 633 nm
Legal Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
48-0032 Anti-Mouse CD3 eFluor® 450 405 nm 450 nm FC RUO
14-0032 Anti-Mouse CD3 Purified FC, IHC, FA RUO
17-0032 Anti-Mouse CD3 APC 633 nm 660 nm FC RUO
50-0032 Anti-Mouse CD3 eFluor® 660 (Alexa Fluor® 647 Replacement) 633 nm 668 nm FC RUO
47-0032 Anti-Mouse CD3 APC-eFluor® 780 633 nm 780 nm FC RUO
46-0032 Anti-Mouse CD3 PerCP-eFluor® 710 488 nm 710 nm FC RUO
56-0032 Anti-Mouse CD3 Alexa Fluor® 700 633 nm 723 nm FC RUO
16-0032 Anti-Mouse CD3 Functional Grade Purified FC, FA RUO
References

References: Miescher, G. C., M. Schreyer, et al. Production and characterization of a rat monoclonal antibody against the murine CD3 molecular complex. Immunol Lett. 1989: 23(2): 113-8.

Zhang Y, McCormick LL, Desai SR, Wu C, Gilliam AC. Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation.J Immunol. 2002 Mar 15;168(6):3088-98.(17A2, IH/F, PubMed)

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