Anti-Mouse CD2 Biotin

Description: The RM2-5 monoclonal antibody reacts with the mouse CD2 molecule, an approximately 50-55 kDa cell surface receptor expressed by all mouse lymphocytes. Expression of the CD2 antigen in the mouse differs from that of the human in that B lineage cells in the mouse from the pre-B cell stage to mature B cells express CD2. CD2 is a ligand for CD48 in the mouse and is involved in adhesion and activation of T cells.

References:
Nakamura, T., K. Takahashi, et al. (1990). "Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions." J Immunol 145(11): 3628-34.
Yagita, H., T. Nakamura, et al. (1989). "CD2 expression in murine B cell lineage." Int Immunol 1(1): 94-8.
Yagita, H., T. Nakamura, et al. (1989). "Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells." Proc Natl Acad Sci U S A 86(2): 645-9.