Anti-Mouse CD1d Functional Grade Purified

Also known as: CD1.1, Ly-38

Clone: 1B1

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 16-0011

Cat. No.	Size
16-0011-81	50 ug
16-0011-82	100 ug
16-0011-85	500 ug
Please inquire about custom configurations or bulk packaging.

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Staining of BALB/c splenocytes with 1.0 ug of Rat IgG2b kappa Isotype Control Functional Grade...View More

Description

Description: The 1B1 monoclonal antibody reacts with mouse CD1d, a 48 kDa glycoprotein with structural homology to MHC class I molecules. While similar to MHC Class I, CD1d associates with β2-m, functionally CD1d is similar to MHC Class II. 1B1 detects CD1d at varying levels on mouse leukocytes. 1B1 detects β2-m associated CD1d.

Details

Host	Rat
Isotype	IgG2b, kappa
Reactivity	Mouse
Conjugate	Functional Grade Purified (low endotoxin, azide-free)
Reported Applications	Flow Cytometric Analysis, Functional Assays

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
13-0011	Anti-Mouse CD1d Biotin			FC	RUO
12-0011	Anti-Mouse CD1d PE	488 - 561 nm	575 nm	FC	RUO
53-0011	Anti-Mouse CD1d Alexa Fluor® 488	488 nm	519 nm	FC	RUO
14-0011	Anti-Mouse CD1d Purified			FC, IHC, FA, IP	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
11-4317	Streptavidin FITC	488 nm		FC, ICC, IHC	RUO
11-4811	Anti-Rat IgG FITC	488 nm		FC, ICC, IHC	RUO
12-4317	Streptavidin PE	488 - 561 nm		FC	RUO
13-4813	Anti-Rat IgG Biotin			FC, ELISA, IHC, WB	RUO
16-4031	Rat IgG2b K Isotype Control Functional Grade Purified			FC	RUO
17-4317	Streptavidin APC	633 - 647 nm	660 nm	FC	RUO

References

References:
Brossay L, D.Jullien, S. Cardell, B.C. Sydora, N. Burdin, R.L. Modlin, and M. Kronenberg. 1997. Mouse CD1 is mainly expressed on hemopoietic derived cells. J. Immunol. 159: 1216-1224.
Amano M., N. Baumgarth, M.D. Dick, L. Brossay, M. Kronenberg, L.A. Herzenberg, and S Strober. 1998. CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: beta2-microglobulin-dependent and independent forms. J. Immunol. 161:1710-1717.
Sydora B.C., L. Brossay, A. Hagenbaugh, M. Kronenberg, and H. Cheroutre. 1996. TAP-independent selection of CD8+ intestinal intraepithelial lymphocytes. J. Immunol. 156: 4209-4216.
Roark J.H., S.-H. Park, J. Jayawardena, U. Kavita, M. Shannon, and A. Bendelac. 1998. CD1.1 expression by mouse antigen-presenting cells and marginal zone B cells. J. Immunol. 160: 3121-3127.
Kawano, T. J. Cui, Y. Koezuka, I. Toura, Y. Kaneko, K. Motoki, H. Ueno, R. Nakagawa, H. Sato, E. Kondo, H. Koseki, and M. Taniguchi. 1997. CD1d-restricted and TCR-mediated activation of Valpha14 NKT cells by glycosylceramides. Science 278:1626-1629.
Brudin N., L. Brossay, Y. Koezuka, S. T. Smiley, M. J. Grusby, M. Gui, M. Taniguchi, K. Hayakawa, M. Kronenberg. 1998. Selective Ability of Mouse CD1 to Present Glycolipids: alpha-Galactosylceramide Specifically Stimulates Valpha14+ NK T Lymphocytes. J. Immunol 161: 271-81.
Szalay G, Ladel CH, Blum C, Brossay L, Kronenberg M, Kaufmann SH. Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF-beta 2 and Th1 cytokines and ameliorates listeriosis in mice. J Immunol. 1999 Jun 15;162(12):6955-8. (in vivo, PubMed)

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD1d	Innate Immunity	Dendritic Cells	Functional Grade Purified