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Anti-Mouse CD19 Super Bright 600

Clone: eBio1D3 (1D3)

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 63-0193

Cat. No. Size
63-0193-80 25 ug
63-0193-82 100 ug

Data for Anti-Mouse CD19 Super Bright 600.

Staining of C57Bl/6 splenocytes with Anti-Mouse CD3 APC (cat. 17-0032) and 0.25 ug of Rat IgG2a K...View More

  • Data for Anti-Mouse CD19 Super Bright 600.
Description

Description: The eBio1D3 (1D3) monoclonal antibody reacts with mouse CD19, a 95 kDa transmembrane glycoprotein. CD19 is expressed by B cells during all stages of development excluding the terminally differentiated plasma cells. Follicular dendritic cells also express CD19. Together CD21, CD81, MHC class II, and CD19 form a multimolecular complex that associates with the BCR. Signaling through CD19 induces tyrosine phosphorylation, calcium flux and proliferation of B cells.

Details
Host Rat
Isotype IgG2a, kappa
Reactivity Mouse
Conjugate Super Bright 600
Laser Violet Laser
Emit 600 nm
Excite 405 nm
Legal Patent pending.
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
13-0193 Anti-Mouse CD19 Biotin FC RUO
48-0193 Anti-Mouse CD19 eFluor® 450 405 nm 445 nm FC RUO
50-0193 Anti-Mouse CD19 eFluor® 660 633 - 647 nm 668 nm FC RUO
15-0193 Anti-Mouse CD19 PE-Cyanine5 488 - 561 nm 667 nm FC RUO
35-0193 Anti-Mouse CD19 PE-Cyanine5.5 488 - 567 nm 690 nm FC RUO
14-0193 Anti-Mouse CD19 Purified FC, IHC, IHC-F, FA, IP RUO
17-0193 Anti-Mouse CD19 APC 633 - 647 nm 660 nm FC RUO
69-0193 Anti-Mouse CD19 eFluor® 506 405 nm 506 nm FC RUO
45-0193 Anti-Mouse CD19 PerCP-Cyanine5.5 488 nm 695 nm FC RUO
11-0193 Anti-Mouse CD19 FITC 488 nm 520 nm FC RUO
47-0193 Anti-Mouse CD19 APC-eFluor® 780 633 - 647 nm 780 nm FC RUO
16-0193 Anti-Mouse CD19 Functional Grade Purified FC, IHC, IHC-F, FA RUO
25-0193 Anti-Mouse CD19 PE-Cyanine7 488 - 561 nm 775 nm FC RUO
56-0193 Anti-Mouse CD19 Alexa Fluor® 700 633 - 647 nm 723 nm FC RUO
12-0193 Anti-Mouse CD19 PE 488 - 561 nm 578 nm FC RUO
83-0193 Anti-Mouse CD19 eVolve™ 605 605 nm FC RUO
61-0193 Anti-Mouse CD19 PE-eFluor® 610 488 - 561 nm 607 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
63-4321 Rat IgG2a K Isotype Control Super Bright 600 405 nm 600 nm FC RUO
17-0032 Anti-Mouse CD3 APC 633 - 647 nm 660 nm FC RUO
SB-4400 Super Bright Staining Buffer FC GPR
References

References: Cherukuri A, Cheng PC, Pierce SK. The role of the CD19/CD21 complex in B cell processing and presentation of complement-tagged antigens. J Immunol. 2001 Jul 1;167(1):163-72.

Inabe K, Kurosaki T. Tyrosine phosphorylation of B-cell adaptor for phosphoinositide 3-kinase is required for Akt activation in response to CD19 engagement. Blood. 2002 Jan 15;99(2):584-9.

Krop I, de Fougerolles AR, Hardy RR, Allison M, Schlissel MS, Fearon DT. Self-renewal of B-1 lymphocytes is dependent on CD19. Eur J Immunol. 1996 Jan;26(1):238-42. (1D3, FA, PubMed)

Shoham T, Rajapaksa R, Boucheix C, Rubinstein E, Poe JC, Tedder TF, Levy S. The tetraspanin CD81 regulates the expression of CD19 during B cell development in a postendoplasmic reticulum compartment. J Immunol. 2003 Oct 15;171(8):4062-72.

Krop I, Shaffer AL, Fearon DT, Schlissel MS. The signaling activity of murine CD19 is regulated during cell development. J Immunol. 1996 Jul 1;157(1):48-56. (1D3, FC, FA, PubMed)


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