Anti-Mouse CD153 Biotin

Also known as: CD30 Ligand, CD30L, TNFSF8

Clone: RM153

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 13-1531

Cat. No. Size
13-1531-81 50 ug
13-1531-82 100 ug
13-1531-85 500 ug
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Data for Anti-Mouse CD153 Biotin.

Staining of ConA-stimulated mouse splenocytes with Anti-Mouse CD153 PE. Appropriate isotype...View More

  • Data for Anti-Mouse CD153 Biotin.
Description

Description: The RM153 monoclonal antibody reacts with mouse CD153 (CD30 ligand). This 40 kDa cell surface receptor, a type II transmembrane protein, is a member of the TNF superfamily. Interaction of CD30 with CD153 plays an important role in T cell activation/costimulation. Expression of CD153 on T cells does not appear to require costimulation through CD28 and is upregulated via TCR engagement and peaks 24-48 hours after activation. Signaling through CD153 is important in costimulation of pre-activated T cells.

Details
Host Rat
Isotype IgG2b, kappa
Reactivity Mouse
Conjugate Biotin
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
16-1531 Anti-Mouse CD153 Functional Grade Purified FC, FA RUO
12-1531 Anti-Mouse CD153 PE 488 - 561 nm 575 nm FC RUO
14-1531 Anti-Mouse CD153 Purified FC, IHC, FA, IP RUO
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17-4317 Streptavidin APC 633 - 647 nm 660 nm FC RUO
References

References:
Shimozato, O., K. Takeda, et al. (1999). "Expression of CD30 ligand (CD153) on murine activated T cells." Biochem Biophys Res Commun 256(3): 519-26.


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