Anti-Mouse CD14 PE-Cyanine7

Clone: Sa2-8

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 25-0141

Cat. No.	Size
25-0141-80	25 ug
25-0141-82	100 ug
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Staining of mouse thioglycolate-elicited peritoneal exudate cells with 0.5 ug of Rat IgG2a K Isotype...View More

Description

Description: The Sa2-8 monoclonal antibody reacts with mouse CD14, a 53-55 kDa GPI-linked glycoprotein. CD14 is a receptor for the complexes of LPS and LBP (LPS-Binding Protein) and is shown to associate with Toll-Like Receptor 4 (TLR4) and participate in the signaling and cellular response to bacterial LPS. In mouse, CD14 is expressed on the surface of macrophages and under certain conditions is also found in the serum in a secreted form. Sa2-8 has weak antagonistic activity (in NF-kappaB activation or TNF alpha production with LPS stimulation).

Details

Host	Rat
Isotype	IgG2a, kappa
Reactivity	Mouse
Conjugate	PE-Cyanine7
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Emit	775 nm
Excite	488 - 561 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
16-0141	Anti-Mouse CD14 Functional Grade Purified			FC	RUO
45-0141	Anti-Mouse CD14 PerCP-Cyanine5.5	488 nm		FC	RUO
46-0141	Anti-Mouse CD14 PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
14-0141	Anti-Mouse CD14 Purified			FC, IP, WB	RUO
17-0141	Anti-Mouse CD14 APC	633 - 647 nm	660 nm	FC	RUO
12-0141	Anti-Mouse CD14 PE	488 - 561 nm	575 nm	FC	RUO
11-0141	Anti-Mouse CD14 FITC	488 nm	518 nm	FC	RUO
13-0141	Anti-Mouse CD14 Biotin			FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
16-0161	Anti-Mouse CD16/CD32 Functional Grade Purified			FC, FA	RUO
25-4321	Rat IgG2a K Isotype Control PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO
45-4801	Anti-Mouse F4/80 Antigen PerCP-Cyanine5.5	488 nm		FC	RUO

References

References: Akashi S, Saitoh S, Wakabayashi Y, Kikuchi T, Takamura N, Nagai Y, Kusumoto Y, Fukase K, Kusumoto S, Adachi Y, Kosugi A, Miyake K. Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14. J Exp Med. 2003 198(7): 1035-42.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD14	Innate Immunity	Macrophage & Monocyte Cells	PE-Cyanine7