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SKU# 16-0141
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Description: The Sa2-8 monoclonal antibody reacts with mouse CD14, a 53-55 kDa GPI-linked glycoprotein. CD14 is a receptor for the complexes of LPS and LBP (LPS-Binding Protein) and is shown to associate with Toll-Like Receptor 4 (TLR4) and participate in the signaling and cellular response to bacterial LPS. In mouse, CD14 is expressed on the surface of macrophages and under certain conditions is also found in the serum in a secreted form. Sa2-8 has weak antagonistic activity (in NF-κB activation or TNF-α production with LPS stimulation).
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References: Akashi S, Saitoh S, Wakabayashi Y, Kikuchi T, Takamura N, Nagai Y, Kusumoto Y, Fukase K, Kusumoto S, Adachi Y, Kosugi A, Miyake K. 2003. Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14. J Exp Med. 198(7): 1035-42.
Anti-Human IL-4 Purified
Anti-Human TCL1 Alexa 647 (Refer APC format cat. 17-6699)
Rat IgG2a K Isotype Control PE
Anti-Human CD205 PE
Mouse IgG1 K Isotype Control Alexa Fluor® 488