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Anti-Mouse CD117 (c-Kit) Super Bright 436

Also known as: Steel Factor Receptor

Clone: 2B8

RUO: For Research Use Only. Not for use in diagnostic procedures.

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SKU# 62-1171

Cat. No. Size
62-1171-80 25 ug
62-1171-82 100 ug

Data for Anti-Mouse CD117 (c-Kit) Super Bright 436.

Staining of C57Bl/6 bone marrow cells with Anti-Mouse Ly-6A/E (Sca-1) PE (cat. 12-5981) and 0.03 ug...View More

  • Data for Anti-Mouse CD117 (c-Kit) Super Bright 436.
Description

Description: The 2B8 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor, and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145-kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1 low) and negative for lineage markers. The interaction of the mouse c-Kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells.

Details
Host Rat
Isotype IgG2b, kappa
Reactivity Mouse, Pig
Conjugate Super Bright 436
Laser Violet Laser
Emit 436 nm
Excite 405 nm
Legal Patent pending.
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
17-1171 Anti-Mouse CD117 (c-Kit) APC 633 - 647 nm 660 nm FC RUO
13-1171 Anti-Mouse CD117 (c-Kit) Biotin FC RUO
19-1171 Anti-Mouse CD117 (c-Kit) Cyanine5 (Discontinued) 633 - 647 nm 670 nm FC RUO
61-1171 Anti-Mouse CD117 (c-Kit) PE-eFluor® 610 488 - 561 nm 607 nm FC RUO
11-1171 Anti-Mouse CD117 (c-Kit) FITC 488 nm 520 nm FC RUO
47-1171 Anti-Mouse CD117 (c-Kit) APC-eFluor® 780 633 - 647 nm 780 nm FC RUO
48-1171 Anti-Mouse CD117 (c-Kit) eFluor® 450 405 nm 445 nm FC RUO
46-1171 Anti-Mouse CD117 (c-Kit) PerCP-eFluor® 710 488 nm 710 nm FC RUO
25-1171 Anti-Mouse CD117 (c-Kit) PE-Cyanine7 488 - 561 nm 775 nm FC RUO
12-1171 Anti-Mouse CD117 (c-Kit) PE 488 - 561 nm 578 nm FC RUO
15-1171 Anti-Mouse CD117 (c-Kit) PE-Cyanine5 488 - 561 nm 667 nm FC RUO
14-1171 Anti-Mouse CD117 (c-Kit) Purified FC, IP RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
62-4031 Rat IgG2b K Isotype Control Super Bright 436 405 nm 436 nm FC RUO
12-5981 Anti-Mouse Ly-6A/E (Sca-1) PE 488 - 561 nm 578 nm FC RUO
SB-4400 Super Bright Staining Buffer FC GPR
References

References: Ikuta K, Weissman IL. 1992. Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation. Proc Natl Acad Sci USA. 89(4): 1502-6.