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Anti-Mouse CD117 (c-Kit) Cy5

Also known as: cKit, Steel Factor Receptor, Mast/stem cell growth factor receptor, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit

Clone: 2B8

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 19-1171

Cat. No. Size
19-1171-81 50 ug
19-1171-82 100 ug
19-1171-83 200 ug
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Data for Anti-Mouse CD117 (c-Kit) Cy5.

Staining of C57BL/6 bone marrow cells with Anti-Human/Mouse CD45R (B220) FITC (cat. 11-0452) and...View More

  • Data for Anti-Mouse CD117 (c-Kit) Cy5.
Description

Description: The 2B8 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145 kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells.

Details
Host Rat
Isotype IgG2b, kappa
Reactivity Mouse
Conjugate Cy5
Laser Red Laser
Emit 670 nm
Excite 633 - 647 nm
Legal FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
13-1171 Anti-Mouse CD117 (c-Kit) Biotin FC RUO
14-1171 Anti-Mouse CD117 (c-Kit) Purified FC, IP RUO
25-1171 Anti-Mouse CD117 (c-Kit) PE-Cy7 488 nm 760 nm FC RUO
17-1171 Anti-Mouse CD117 (c-Kit) APC 633 - 647 nm 660 nm FC RUO
15-1171 Anti-Mouse CD117 (c-Kit) PE-Cy5 488 - 561 nm 670 nm FC RUO
46-1171 Anti-Mouse CD117 (c-Kit) PerCP-eFluor® 710 (PE-Cy5.5 replacement) 488 nm 710 nm FC RUO
11-1171 Anti-Mouse CD117 (c-Kit) FITC 488 nm 518 nm FC RUO
47-1171 Anti-Mouse CD117 (c-Kit) APC-eFluor® 780 633 nm 780 nm FC RUO
12-1171 Anti-Mouse CD117 (c-Kit) PE 488 - 561 nm 575 nm FC RUO
References

References: Ikuta K, Weissman IL. 1992. Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation. Proc Natl Acad Sci USA. 89(4): 1502-6.

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