Anti-Mouse CD115 (c-fms) Purified

Also known as: CSF-1-R, FMS, Colony-Stimulating Factor 1 Receptor, M-CSF Receptor, CSF1R

Clone: AFS98

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-1152

Cat. No. Size
14-1152-81 50 ug
14-1152-85 500 ug
14-1152-82 100 ug
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Data for Anti-Mouse CD115 (c-fms) Purified.

Staining of thioglycolate-induced peritoneal exudate cells (PECs) with 0.25 ug of Rat IgG2a kappa...View More

  • Data for Anti-Mouse CD115 (c-fms) Purified.
Description

Description: The AFS98 monoclonal antibody reacts with the mouse CD115 molecule, a receptor for macrophage colony stimulating factor (M-CSF) or colony stimulating factor-1 (CSF-1). CD115 is expressed by monocyte, macrophage, osteoclast, and some epithelial cells. It is a 150 kDa c-fms gene product and belongs to immunoglobulin family. CSF-1 signaling through CSF-1R regulates the proliferation and differentiation of cells in the monocytic lineage.

Details
Host Rat
Isotype IgG2a, kappa
Reactivity Mouse
Conjugate Purified
Reported Applications Flow Cytometric Analysis, Immunohistochemical Staining of Frozen Tissue Sections, Functional Assays, Western Blotting
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
53-1152 Anti-Mouse CD115 (c-fms) Alexa Fluor® 488 488 nm 519 nm FC RUO
61-1152 Anti-Mouse CD115 (c-fms) PE-eFluor® 610 488 - 561 nm 607 nm FC RUO
46-1152 Anti-Mouse CD115 (c-fms) PerCP-eFluor® 710 488 nm 710 nm FC RUO
16-1152 Anti-Mouse CD115 (c-fms) Functional Grade Purified FC, FA RUO
25-1152 Anti-Mouse CD115 (c-fms) PE-Cyanine7 488 - 561 nm 775 nm FC RUO
13-1152 Anti-Mouse CD115 (c-fms) Biotin FC RUO
12-1152 Anti-Mouse CD115 (c-fms) PE 488 - 561 nm FC RUO
17-1152 Anti-Mouse CD115 (c-fms) APC 633 - 647 nm 660 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
11-4317 Streptavidin FITC 488 nm FC, ICC, IHC RUO
12-4317 Streptavidin PE 488 - 561 nm FC RUO
14-4321 Rat IgG2a K Isotype Control Purified FC, ICC, IHC RUO
11-4811 Anti-Rat IgG FITC 488 nm FC, ICC, IHC RUO
13-4813 Anti-Rat IgG Biotin FC, ELISA, IHC, WB RUO
17-4317 Streptavidin APC 633 - 647 nm 660 nm FC RUO
References

References: Murayama T, Yokode M, et al. 1999. Intraperitoneal administration of anti-c-fms monoclonal antibody prevents initial events of atherogenesis but does not reduce the size of advanced lesions in apolipoprotein E-deficient mice. Circulation. 99(13): 1740-6.

Sudo T, Nishikawa S, et al. 1995. Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M. Oncogene. 11(12): 2469-76.