Anti-Mouse CD115 (c-fms) APC

Also known as: CSF-1-R, FMS, Colony-Stimulating Factor 1 Receptor, M-CSF Receptor, CSF1R

Clone: AFS98

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 17-1152

Cat. No.	Size
17-1152-80	25 ug
17-1152-82	100 ug
Please inquire about custom configurations or bulk packaging.

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Staining of thioglycolate-induced peritoneal exudate cells (PECs) with 0.03 ug of Rat IgG2a kappa...View More

Description

Description: The AFS98 monoclonal antibody reacts with the mouse CD115 molecule, a receptor for macrophage colony stimulating factor (M-CSF) or colony stimulating factor-1 (CSF-1). CD115 is expressed by monocyte, macrophage, osteoclast, and some epithelial cells. It is a 150 kDa c-fms gene product and belongs to immunoglobulin family. CSF-1 signaling through CSF-1R regulates the proliferation and differentiation of cells in the monocytic lineage.

Details

Host	Rat
Isotype	IgG2a, kappa
Reactivity	Mouse
Conjugate	APC
Laser	Red Laser
Emit	660 nm
Excite	633 - 647 nm
Reported Applications	Flow Cytometric Analysis

Documentation

For complete product information, please download the TDS or IFU document.

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
12-1152	Anti-Mouse CD115 (c-fms) PE	488 - 561 nm	575 nm	FC	RUO
46-1152	Anti-Mouse CD115 (c-fms) PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
53-1152	Anti-Mouse CD115 (c-fms) Alexa Fluor® 488	488 nm	519 nm	FC	RUO
14-1152	Anti-Mouse CD115 (c-fms) Purified			FC, IHC, FA, WB	RUO
13-1152	Anti-Mouse CD115 (c-fms) Biotin			FC	RUO
16-1152	Anti-Mouse CD115 (c-fms) Functional Grade Purified			FC, FA	RUO

References

References: Murayama T, Yokode M, et al. 1999. Intraperitoneal administration of anti-c-fms monoclonal antibody prevents initial events of atherogenesis but does not reduce the size of advanced lesions in apolipoprotein E-deficient mice. Circulation. 99(13): 1740-6.

Sudo T, Nishikawa S, et al. 1995. Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M. Oncogene. 11(12): 2469-76.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD115 (c-fms)	Cell Signaling Cytokines, Chemokines, Growth Factors Innate Immunity Angiogenesis	Macrophage & Monocyte Cells	APC