Anti-Mouse CD115 (c-fms) Alexa Fluor® 488

Also known as: CSF-1-R, FMS, Colony-Stimulating Factor 1 Receptor, M-CSF Receptor, CSF1R

Clone: AFS98

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 53-1152

Cat. No.	Size
53-1152-80	25 ug
53-1152-82	100 ug
Please inquire about custom configurations or bulk packaging.

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Staining of thioglycolate-induced peritoneal exudeate cells (PECs) with 0.25 ug of Rat IgG2a kappa...View More

Description

Description: The AFS98 monoclonal antibody reacts with the mouse CD115 molecule, a receptor for macrophage colony stimulating factor (M-CSF) or colony stimulating factor-1 (CSF-1). CD115 is expressed by monocyte, macrophage, osteoclast, and some epithelial cells. It is a 150 kDa c-fms gene product and belongs to immunoglobulin family. CSF-1 signaling through CSF-1R regulates the proliferation and differentiation of cells in the monocytic lineage.

Details

Host	Rat
Isotype	IgG2a, kappa
Reactivity	Mouse
Conjugate	Alexa Fluor 488
Laser	Blue Laser
Emit	519 nm
Excite	488 nm
Legal	Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications	Flow Cytometric Analysis

Documentation

For complete product information, please download the TDS or IFU document.

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
14-1152	Anti-Mouse CD115 (c-fms) Purified			FC, IHC, FA, WB	RUO
17-1152	Anti-Mouse CD115 (c-fms) APC	633 - 647 nm	660 nm	FC	RUO
16-1152	Anti-Mouse CD115 (c-fms) Functional Grade Purified			FC, FA	RUO
13-1152	Anti-Mouse CD115 (c-fms) Biotin			FC	RUO
46-1152	Anti-Mouse CD115 (c-fms) PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
12-1152	Anti-Mouse CD115 (c-fms) PE	488 - 561 nm	575 nm	FC	RUO

References

References: Murayama T, Yokode M, et al. 1999. Intraperitoneal administration of anti-c-fms monoclonal antibody prevents initial events of atherogenesis but does not reduce the size of advanced lesions in apolipoprotein E-deficient mice. Circulation. 99(13): 1740-6.

Sudo T, Nishikawa S, et al. 1995. Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M. Oncogene. 11(12): 2469-76.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD115 (c-fms)	Cell Signaling Cytokines, Chemokines, Growth Factors Innate Immunity Angiogenesis	Macrophage & Monocyte Cells	Alexa Fluor 488