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Anti-Mouse CD106 (VCAM-1) Alexa Fluor® 647 (To Be Discontinued. Refer to Cat. No. 50-1061)

Also known as: VCAM1, vascular cell adhesion molecule-1

Clone: 429

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 51-1061

Cat. No. Size
51-1061-80 25 ug
51-1061-82 100 ug
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Data for Anti-Mouse CD106 (VCAM-1) Alexa Fluor® 647.

Staining of C57BL/6 bone marrow cells with 0.25 ug of Rat IgG2a kappa Isotype Control Alexa Fluor®...View More

  • Data for Anti-Mouse CD106 (VCAM-1) Alexa Fluor® 647.
Description

Description: The 429 monoclonal antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.

Details
Host Rat
Isotype IgG2a, kappa
Reactivity Mouse
Conjugate Alexa Fluor 647
Laser Red Laser
Emit 668 nm
Excite 633 nm
Legal Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
48-1061 Anti-Mouse CD106 (VCAM-1) eFluor® 450 405 nm 450 nm FC RUO
16-1061 Anti-Mouse CD106 (VCAM-1) Functional Grade Purified FC, FA RUO
13-1061 Anti-Mouse CD106 (VCAM-1) Biotin FC RUO
IH93-1061 Anti-Mouse CD106 (VCAM-1) eFluor® 605NC (for IHC/ICC) 350 - 590 nm 605 nm ICC, IHC RUO
11-1061 Anti-Mouse CD106 (VCAM-1) FITC 488 nm 518 nm FC RUO
50-1061 Anti-Mouse CD106 (VCAM-1) eFluor® 660 (Alexa Fluor® 647 Replacement) 633 nm 668 nm FC RUO
14-1061 Anti-Mouse CD106 (VCAM-1) Purified FC, IHC, FA, IP RUO
References

References:
Kinashi, T., Y. St. Pierre, et al. (1995).Expression of glycophosphatidylinositol-anchored and -non-anchored isoforms of vascular cell adhesion molecule 1 in murine stromal and endothelial cells. J Leukoc Biol 57(1): 168-73.

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